Molecular Evolution A Phylogenetic Approach

by Page, Roderick D.M.; Holmes, Edward C.

• ISBN13: 9780865428898
• ISBN10: 0865428891
• Edition: 1st
• Format: Paperback
• Copyright: 1991-01-16
• Publisher: Wiley-Blackwell

Summary

The study of evolution at the molecular level has given the subject of evolutionary biology a new significance. Phylogenetic 'trees' of gene sequences are a powerful tool for recovering evolutionary relationships among species, and can be used to answer a broad range of evolutionary and ecological questions. They are also beginning to permeate the medical sciences. In this book, the authors approach the study of molecular evolution with the phylogenetic tree as a central metaphor. This will equip students and professionals with the ability to see both the evolutionary relevance of molecular data, and the significance evolutionary theory has for molecular studies. The book is accessible yet sufficiently detailed and explicit so that the student can learn the mechanics of the procedures discussed. The book is intended for senior undergraduate and graduate students taking courses in molecular evolution/phylogenetic reconstruction. It will also be a useful supplement for students taking wider courses in evolution, as well as a valuable resource for professionals. First student textbook of phylogenetic reconstruction which uses the tree as a central metaphor of evolution. Chapter summaries and annotated suggestions for further reading. Worked examples facilitate understanding of some of the more complex issues. Emphasis on clarity and accessibility.

Author Biography

Roderic Dugald Morton Page, known as Rod, is an evolutionary biologist at the University of Glasgow, Scotland, and the author of several books. As of 2015 he is professor at the University of Glasgow and was editor of the journal Systematic Biology until the end of 2007. Edward Charles Holmes FRS FAA is an evolutionary biologist and virologist, and since 2012 an National Health and Medical Research Council Australia Fellow and professor at the University of Sydney.

Table of Contents

Acknowledgements	v
1 The Archaeology of the Genome	1	(10)
2 Trees	11	(26)
3 Genes: Organisation, Function and Evolution	37	(52)
4 Genes in Populations	89	(46)
5 Measuring Genetic Change	135	(37)
6 Inferring Molecular Phylogeny	172	(56)
7 Models of Molecular Evolution	228	(52)
8 Applications of Molecular Phylogenetics	280	(35)
References and Bibliography	315	(20)
Index	335