Multiscale Modeling of Particle Interactions Applications in Biology and Nanotechnology

by King, Michael; Gee, David

• ISBN13: 9780470242353
• ISBN10: 0470242353
• Edition: 1st
• Format: Hardcover
• Copyright: 2010-03-22
• Publisher: Wiley

Summary

Computational biology and nanotechnology have become critical elements in particle interactions, especially in biological sciences, medicine, toxicology, and technology. Multiscale Modeling of Particle Interactions provides vital insight on particle interactions in areas of biological sciences, chemical engineering, medicine, and manufacturing technology. To better examine cell and tissue mechanics, theoretical aspects of multiscale modeling, and new developments in nanotechnology, the text includes real experimental data and images from novel optical microscopy systems. Chemists and biologists as well as clinicians and students will find this a helpful and important reference.

Author Biography

Michael R. King, PhD, is an Associate Professor of Biomedical Engineering at Cornell University. King is an expert on the receptor-mediated adhesion of circulating cells, and has developed new computational and in vitro models to study the function of leukocytes, platelets, and stem, stem and cancer cells under flow. He is a former Whitaker investigator, a James D. Watson Investigator of New York State, and an NSF CAREER Award recipient. King received the 2008 ICNMM Outstanding Researcher Award from the American Society of Mechanical Engineers, was the 2007-2008 Professor of the Year in Engineering at the University of Rochester, and received the 2009 Outstanding Contribution for a Publication in the international journal clinical Chemistry. David J. Gee, PhD, is an Assistant Professor of Mechanical Engineering at the Rochester Institute of Technology, where he studies the inflammatory response and investigates applications in receptor-mediated adhesion. Previously, Dr. Gee was a research assistant professor and postdoctoral fellow in the Department of Biomedical Engineering at the University of Rochester, where he studied inflammation, and has also served as a research engineer at the Institute for Advanced Technology at The University of Texas at Austin, where he specialized in impact mechanics and computational solid mechanics.

Table of Contents

Contributors	p. vii
Introduction	p. 1
Applications in Nanotechnology	p. 5
Multiscale Modeling of Nanoscale Aggregation Phenomena: Applications in Semiconductor Materials Processing	p. 7
Multiscale Modeling of Rare Events in Self-Assembled Systems	p. 41
Continuum Description of Atomic Sheets	p. 79
Coulombic Dragging and Mechanical Propelling of Molecules in Nanofluidic Systems	p. 117
Molecular Dynamics Modeling of Nanodroplets and Nanoparticles	p. 151
Modeling the Interactions Between Compliant Microcapsules and Patterned Surfaces	p. 185
yApplications in Biology	p. 223
Coarse-Grained and Multiscale Simulations of Lipid Bilayers	p. 225
Stochastic Approach to Biochemical Kinetics	p. 243
In Silico Modeling of Angiogenesis at Multiple Scales: From Nanoscale to Organ System	p. 287
Large-Scale Simulation of Blood Flow in Microvessels	p. 321
Molecular to Multicellular Deformation During Adhesion of Immune Cells Under Flow	p. 341
Index	p. 369
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