Mutation: The History of an Idea from Darwin to Genomics

by Carlson, Elof Axel

• ISBN13: 9781936113309
• ISBN10: 1936113309
• Format: Hardcover
• Copyright: 2011-06-03
• Publisher: Cold Spring Harbor Laboratory Press

Summary

The idea of mutation has changed considerably from the pre-Mendelian concepts of Darwin's generation to today's up-to-the-minute genomic context of mutation. The historical approach taken by History of Mutation reveals the way science works, incrementally by small steps rather than by dramatic, and rare, paradigm shifts.

Table of Contents

Preface	p. vii
A Brief Overview of the Concept of Mutation	p. 1
Ideas of Mutation before There Was a Mendelian Basis for Genetics	p. 11
Cytological and Mendelian Aspects of Mutation	p. 23
The Fly Lab Redefines Mutation	p. 41
Radiation and the Analysis of Mutation by Mutagenesis	p. 55
Using Biochemical Approaches to Study Mutation	p. 69
Mutation in Relation to Gene Structure	p. 85
Mutation in Relation to Evolution	p. 97
Mutation in Relation to Genetic Engineering	p. 115
Mutation in Relation to Society	p. 127
Mutation in Relation to History and Philosophy of Science	p. 139
Glossary of Terms Associated with Mutation	p. 147
Index	p. 159
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