Myelodysplastic Syndromes: Clinical and Biological Advances

by Edited by Peter L. Greenberg

• ISBN13: 9780521182287
• ISBN10: 052118228X
• Edition: Revised
• Format: Paperback
• Copyright: 2011-02-17
• Publisher: Cambridge University Press

Summary

Myelodysplastic Syndromes was first published in 2006, and continues to stand out as the definitive text on the genetics, pathophysiology, and clinical management of this wide range of syndromes. It remains a major reference on all aspects of the clinical classification underlying pathogenetic mechanisms and treatment of the myelodysplastic syndromes. Authored by international experts, the book provides an assessment of the subject's status and a variety of advances in the field. The chapters cover all aspects of the myelodysplastic syndromes, from an in-depth analysis of the multifactorial nature of this disease, including a careful assessment of stromal, immunological and stem cell abnormalities, to a review of recent molecular and cytogenetic discoveries and insights. This book will be a valuable resource to clinicians and researchers who wish to learn more about myelodysplastic syndromes.

Table of Contents

Preface Peter Greenberg

Clinical and prognostic characterization of Myelodysplastic Syndrome

Morphologic classifications of Myelodysplastic Syndrome: French-American-British and the World Health Organization

Pathogenetic mechanisms underlying Myelodysplastic Syndrome

Cytogenetic abnormalities in Myelodysplastic Syndrome

Molecular mechanisms and gene expression patterns in Myelodysplastic Syndrome

Immunologic mechanisms and treatment of Myelodysplastic Syndrome

Biologically targeted therapies for Myelodysplastic Syndrome

Supportive care in Myelodysplastic Syndrome: hemopoietic cytokines and iron chelation therapy

Hematopoietic cell transplantation options in Myelodysplastic Syndrome

Health-related quality of life in Myelodysplastic Syndrome: conceptualization, measurement and implications

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