Nanomaterials for Medical Diagnosis and Therapy

by Kumar, Challa S. S. R.

• ISBN13: 9783527313907
• ISBN10: 3527313907
• Edition: 1st
• Format: Hardcover
• Copyright: 2007-04-16
• Publisher: Wiley-VCH

Summary

Following an overview of nanotechnologies for diagnostic purposes, this book goes on to look at nanoparticle-based magnetic resonance, molecular and other imaging applications, as well as the potential roles of carbon nanotubes and bionanoparticles in biomedical applications. The book's main focus is on drug delivery systems based on nonporous and nanosize materials, solid lipid and polymeric nanoparticles, intelligent hydrogels, core-shell nanoparticles, and nanocapsules, rounded off by a discussion of their biomedical applications. The final part of this volume covers such biomedical strategies as gene therapy, synthetic gene-transfer vectors and targeted delivery.

Author Biography

Challa Kumar is currently the Group Leader of Nanofabrication at the Center for Advanced Microstructures and Devices (CAMD), Baton Rouge, USA. His research interests are in developing novel synthetic methods for functional nanomaterials and innovative therapeutic, diagnostic and sensory tools based on nanotechnology. He has eight years of industrial R&D experience working for Imperial Chemical Industries and United Breweries prior to joining CAMD. He is the founding Editor-in-Chief of the Journal of Biomedical Nanotechnology, an international peer reviewed journal published by American Scientific Publishers, and the series editor for the ten-volume book series Nanotechnologies for the Life Sciences (NtLS) published by Wiley-VCH. He worked at the Max Planck Institute for Biochemistry in Munich, Germany, as a post doctoral fellow and at the Max Planck Institute for Carbon Research in Mulheim, Germany, as an invited scientist. He obtained his Ph.D. degree in synthetic organic chemistry from Sri Sathya Sai Institute of Higher Learning, Prashanti Nilayam, India.

Table of Contents

Nanotechnologies for diagnosis - present and future	p. 1
Superparamagnetic nanoparticles of iron oxides for magnetic resonance imaging applications	p. 51
Carbon nanotube-based vectors for delivering immunotherapeutics and drugs	p. 85
Core-shell nanoparticles for drug delivery and molecular imaging	p. 143
Nanotechnologies for targeted delivery of drugs	p. 189
Nanoporous and nanosize materials for drug delivery systems	p. 255
NANOEGG" technology for drug delivery	p. 310
Polymeric nanomaterials - synthesis, functionalization and applications in diagnosis and therapy	p. 342
Polymeric nanoparticles for drug delivery	p. 409
Solid lipid and polymeric nanoparticles for drug delivery	p. 471
Intelligent hydrogels in nanoscale sensing and drug delivery applications	p. 509
Nanoshells for drug delivery	p. 527
Bionanoparticles and their biomedical applications	p. 557
Nanotechnology for gene therapy - HVJ-E vector	p. 597
Nanotoxicology of synthetic gene transfer vectors : poly(ethyleneimine)- and polyfectin-mediated membrane damage and apoptosis in human cell lines	p. 629
Nanoparticles for the treatment of Alzheimer's disease : theoretical rationale, present status and future perspectives	p. 644
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