Neurodevelopment and Adult Psychopathology

by Edited by Matcheri S. Keshavan , Robin M. Murray , Foreword by David Kupfer

• ISBN13: 9780521485654
• ISBN10: 0521485657
• Format: Paperback
• Copyright: 1997-10-13
• Publisher: Cambridge University Press

Summary

In this important book on the role of neurodevelopmental factors in the pathogenesis of the major psychiatric disorders, the fields of developmental neurobiology, clinical psychiatry and behavioural neuroscience are reviewed by an international group of experts, including many of those responsible for the ideas that have come to dominate current thinking. The first section, 'The Developing Brain', reviews neurodevelopment from the molecular to the behavioural level. Section Two, 'Development and Psychopathology', covers clinical applications of the basic principles of developmental neurobiology. The third and final section, 'Integrative Models', presents approaches toward a synthesis of neurodevelopmental and clinical findings in psychiatric disorder. For students, scientists and clinicians in psychiatry, psychology, and neurodevelopment, this is an essential reference.

Table of Contents

Part I. The Developing Brain: 1. Development of the cerebral cortex: an overview Jennifer S. Lund

2. Development of the primate prefrontal cortex David A. Lewis

3. The genetics of neurodevelopment and schizophrenia Astride M. Vicente and James L. Kennedy

4. Glutamate receptors and development anomaly in medial temporal lobe in schizophrenia Robert W. Kerwin et al.

5. MRI studies of developing brain Terry Jernigan and Elizabeth R. Sowell

6.31P magnetic resonance spectroscopy studies of developing brain Jay W. Pettegrew et al.

7. PET studies of developing brain Harry T. Chugani and Diane C. Chugani

8. Long term effects of different early rearing experiences on social, emotional, and physiological development in nonhuman primates Stephen J. Suomi

Part II. Development and Psychopathology: 9. From birth to onset: a developmental perspective of schizophrenia in two national birth cohorts Peter Jones and D. John Done

10. Developmental aspects of schizophrenia Michael F. Pogue-Geile

11. Sex differences in schizophrenia Gretchen L. Haas and David J. Castle

12. Psychopathology and brain dysfunction: structural imaging studies Shon Lewis

13. Neuropathology, neurodevelopment, and schizophrenia Kathryn J. Kotrla et al.

14. Neurodevelopmental models of affective disorders Henry A. Nasrallah

15. Heterogeneity within obsessive compulsive disorder evidence for primary and neurodevelopmental subtypes Tom Blanes and Philip McGuire

16. Schizophrenia: a critique from the devlopmental psychopathology perspectives Chris Hollis and Eric Taylor

Part III. Integrative Models: 17. Schizophrenia as an emergent disorder of late brain maturation Irwin Feinberg

18. Schizophrenia as a developmental disorder of neural network integrity: the dysplastic net hypothesis Ed T. Bullmore et al.

19. Neurodevelopment and schizophrenia: quo vadis? Matcheri S. Keshavan.