Neuroinformatics

by Crasto, Chiquito Joaqium; Koslow, Stephen H.

• ISBN13: 9781588297204
• ISBN10: 1588297209
• Edition: 1st
• Format: Hardcover
• Copyright: 2007-12-30
• Publisher: Humana Pr Inc

Summary

Neuroinformatics presents cutting-edge techniques for the synergistic study of neuroinformatics, thereby facilitating the efforts of discovery neuroscience through the sharing of data and the use of computational models. This book provides the scientific community with the tools and impetus for sharing their research with colleagues around the globe by offering insights, information, and compelling examples of success. This timely volume, nearly a decade and a half after the launch of the Human Brain Project, will help to refocus and enhance current research by informing both new and current Neuroinformatics practitioners. Neuroinformatics is conceptually divided into four sections: Neuroscience Knowledge Management, Computational Neuronal Modeling and Simulations, Imaging, and Neuroinformatics in Genetics and Neurodegenerative Diseases. The contributing authors are all leading researchers in their area of expertise.

Table of Contents

Preface	p. ix
Foreword	p. xi
Contributors	p. xix
Acknowledgments	p. xvii
Color Plates	p. xxiii
Neuroscience Knowledge Management
Managing Knowledge in Neuroscience	p. 3
Interoperability Across Neuroscience Databases	p. 23
Database Architectures for Neuroscience Applications	p. 37
XML for Data Representation and Model Specification in Neuroscience	p. 53
Creating Neuroscience Ontologies	p. 67
Computational Neuronal Modeling and Simulation
Model Structure Analysis in NEURON	p. 91
Constructing Realistic Neural Simulations with GENESIS	p. 103
Simulator for Neural Networks and Action Potentials	p. 127
Data Mining Through Simulation	p. 155
Computational Exploration of Neuron and Neural Network Models in Neurobiology	p. 167
Imaging
Brain Atlases and Neuroanatomic Imaging	p. 183
Brain Mapping with High-Resolution fMRI Technology	p. 195
Brain Spatial Normalization	p. 211
Workflow-Based Approaches to Neuroimaging Analysis	p. 235
Databasing Receptor Distributions in the Brain	p. 267
Neuroinformatics in Genetics and Neurodenegerative Disorders
An Informatics Approach to Systems Neurogenetics	p. 287
Computational Models of Dementia and Neurological Problems	p. 305
Integrating Genetic, Functional Genomic, and Bioinformatics Data in a Systems Biology Approach to Complex Diseases: Application to Schizophrenia	p. 337
Alzforum	p. 365
Index	p. 383
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