Neurological Disorders and Pregnancy

by Minagar

• ISBN13: 9780123849113
• ISBN10: 012384911X
• Edition: 1st
• Format: Hardcover
• Copyright: 2010-12-09
• Publisher: Elsevier Science

Summary

Timely diagnosis and management of neurological diseases during pregnancy poses major therapeutic challenges to neurologists and other non-neurologists health care providers. Pregnancy is a unique period in life which is associated with significant hormonal and other physiologic changes in female patients which may trigger or alter the course of neurological and psychiatric disorders. In addition, many diagnostic procedures which can be performed in non-pregnant women are prohibited during pregnancy for safety reasons. Therapeutic decisions and management of a pregnant patient with neurological disorders heavily depends on the issue of the reasonable balance between the risks of no-treatment versus active treatment for the mother and her fetus.This book provides a review of the latest findings in this field providing both the neurologist and non-neurologist with the information they need in order to determine the best treatment. Neurological disorders covered include multiple sclerosis, stroke and epilepsy. Discusses how neurological disorders should be managed in a pregnant patient Includes contributions from leading authorities

Table of Contents

Preface	p. ix
Contributors	p. xi
Pregnancy and Multiple Sclerosis	p. 1
Introduction	p. 1
How Pregnancy Affects the Disease Activity	p. 2
Pregnancy Outcome Among MS Mothers	p. 3
Treatment of MS Mothers During Pregnancy and Lactation	p. 4
Immunologic Basis of Pregnancy-Induced Disease Remission	p. 6
Conclusion	p. 8
Headache in Pregnancy	p. 13
Introduction	p. 13
Epidemiology of Headache in Pregnancy	p. 13
Pathophysiology of Primary Headache During Pregnancy	p. 18
Management of Primary Headache in Pregnancy	p. 22
Pharmacologic Treatments	p. 25
Secondary Headaches and Their Management	p. 32
Conclusion	p. 44
Myasthenia Gravis and Pregnancy	p. 55
Introduction	p. 55
Clinical Features	p. 55
Diagnosis	p. 56
General Aspects of Preconception Care	p. 57
Effect of Preganancy on MG	p. 57
Effect of MG in Pregnancy	p. 58
Treatment	p. 60
Labor and Delivery	p. 63
Effects on the Fetus and Neonate	p. 65
Postpartum Angiopathy and Related Disorders	p. 69
Background and Context	p. 69
Postpartum Angiopathy	p. 69
Neurology of Pre-eclampsia and Eclampsia	p. 79
Pathophysiology	p. 79
Neurologic Manifestations of Pre-eclampsia/Eclampsia	p. 80
Cerebrovascular Disease	p. 82
Epilepsy	p. 85
Neurobehavioral Aspects of Pre-eclampsia/Eclampsia	p. 87
Epilepsy and Pregnancy	p. 91
Introduction	p. 91
History	p. 92
Fertility and Epilepsy	p. 94
Contraception and Epilepsy	p. 96
The Effect of Pregnancy on Epilepsy	p. 97
The Effects of Epilepsy on Pregnancy	p. 100
Eclampsia	p. 101
Effects of Maternal Seizures on the Developing Fetus	p. 107
Effects of Epilepsy Treatment on the Developing Fetus	p. 108
Evaluation of a First Seizure in a Pregnant Patient	p. 110
Summary	p. 114
Movement Disorders and Pregnancy	p. 123
Introduction	p. 123
Parkinson's Disease	p. 123
Chorea Gravidarum	p. 125
Huntington's Disease	p. 126
Dystonia	p. 126
Essential Tremor	p. 127
Wilson's Disease	p. 128
Restless Legs Syndrome	p. 129
Tourette's Syndrome	p. 129
Conclusions	p. 130
Psychiatric Disorders and Pregnancy	p. 135
Introduction	p. 135
Schizophrenia and Pregnancy	p. 135
Course of Schizophrenia During Pregnancy and Postpartum	p. 137
Antipsychotic Medications and Pregnancy	p. 138
BPD and Pregnancy	p. 143
Postpartum Depression	p. 145
Anxiety Disorders and Pregnancy	p. 147
Eating Disorders and Pregnancy	p. 151
Conclusion	p. 152
Neuromuscular Diseases in Pregnancy	p. 159
Pathophysiology	p. 159
Neuromuscular Diseases that Result from Pregnancy, Labor, and the Postpartum Period	p. 161
Muscle Cramps	p. 166
Pregnancy and Underlying Neuromuscular Disease	p. 166
Inflammatory Neuropathies	p. 167
Hereditary Neuropathies	p. 169
Autoimmune Inflammatory Myopathies	p. 170
Hereditary Myopathies	p. 171
Motor Neuron Diseases	p. 175
Sleep Disorders and Pregnancy	p. 185
Regular Sleep Duration and Pattern in Pregnancy	p. 185
Sleep Deprivation in Pregnancy	p. 186
Sleep-Disordered Breathing in Pregnancy	p. 188
Other Sleep Disorders in Pregnancy	p. 197
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