New Arrhythmia Technologies

by Wang, Paul J.; Naccarelli, Gerald V.; Rosen, Michael R.; Estes, N. A. Mark; Hayes, David L.; Haines, David E.

• ISBN13: 9781405132930
• ISBN10: 1405132930
• Edition: 1st
• Format: Hardcover
• Copyright: 2005-10-28
• Publisher: Wiley-Blackwell

Summary

New Arrhythmia Technologies provides a complete discussion of recent, emerging, and future arrhythmia technologies. This forward-thinking book details successful trials and investigates areas of research that have not yet reached the trial phase. The elite panel of authors have explored fresh information on: bull; bull;advances in antiarrhythmic pharmacologis therapy bull;advances in monitoring, risk assessment, and noninvasive mapping bull;advances in pacing therapy bull;advances in implantable defibrillators bull;advances in catheter and surgical ablation bull;advances in antiarrhythmic biological therapy bull;vision for the future of arrhythmia technologies bull;web-based defibrillation monitoring. New Arrhythmia Technologies presents a unique view of the latest in arrhythmia innovations through the eyes of the experts in the field.

Author Biography

Paul Wang

Dr Paul J Wang is the Director of the Stanford Cardiac Arrhythmia Service and Cardiac Electrophysiology Laboratory. He received his undergraduate degree at Harvard University and his medical degree at Columbia University in New York City. He received his medical residency at Columbia-Presbyterian Medical Center in New York City and completed his cardiovascular training at Brigham and Women's Hospital.

Dr Wang has co-authored textbooks on implantable defibrillators, sudden cardiac death, and cardiac resynchronization/biventricular pacing therapy and has invented a number of new arrhythmia technologies.

He articipates on numerous national boards and panels in cardiac electrophysiology. He is currently Vice-Chair of the Education Committee of the Heart Rhythm Society. He is co-director of an Advanced Course in Pacemakers, Implantable Defibrillators, and Resynchronization Therapy sponsored by the Heart Rhythm Society. He also serves as a member of the Cardiac Electrophysiology Board Certification Exam Writing Committee of the American Board of Internal Medicine.

Table of Contents

List of Contributors	vii
Preface	xiii
Part I Advances in antiarrhythmic pharmacologic therapy
Gerald V. Naccarelli
New antiarrhythmic pharmacologic therapies and regulatory issues in antiarrhythmic drug development	3	(11)
Heather M. Ross
Peter R. Kowey
Gerald V. Naccarelli
New frontiers in antithrombotic therapy for atrial fibrillation	14	(17)
James A. Reiffel
Part II Future of antiarrhythmic therapy
Michael R. Rosen
Principles of pharmacogenomics: Focus on arrhythmias	31	(5)
Dan M. Roden
The cardiac sodium-channel carboxy terminus: predicted and detected structure provide a novel target for antiarrhythmic drugs development	36	(12)
Robert S. Kass
Joseph W. Cormier
Ian W. Glaaser
Embryonic stem-cell-derived cardiomyocytes as a model for arrhythmia	48	(6)
J. Hescheler
M. Halbach
Z.J. Lu
H. Bohlen
B.K. Fleischmann
M. Reppel
Gene and cell therapy for sinus and AV nodal dysfunction	54	(11)
Peter Danilo Jr.
Steven Girouard
Peter R Brink
Ira S. Cohen
Richard B. Robinson
Michael R. Rosen
Gene therapy for cardiac tachyarrhythmias	65	(10)
J. Kevin Donahue
Amy D. McDonald
Alexander Bauer
Kan Kikuchi
Tetsuo Sasano
Part III Monitoring, noninvasive mapping, risk assessment, and external defibrillation
N.A. Mark Estes III
New developments in noninvasive rhythm monitoring, implantable hemodynamic monitoring, functional status monitoring, and noninvasive mapping	75	(9)
Jonathan Weinstock
Munther K. Homoud
Mark S. Link
N.A. Mark Estes III
Techniques of prediction of arrhythmia occurrence and stratification for sudden cardiac death	84	(7)
Aseem D. Desai
Bradley P. Knight
Beta-blocker efficacy in long-QT syndrome patients with mutations in the pore and nonpore regions of the hERG potassium-channel gene	91	(4)
Arthur J. Moss
Derick R. Peterson
Wojciech Zareba
Rahul Seth
Scott A. McNitt
Mark L. Andrews
Ming Qi
Michael J. Ackerman
Jesaia Benhorin
Elizabeth S. Kaufman
Jennifer L. Robinson
Jeffrey A. Towbin
G. Michael Vincent
Li Zhang
New developments in out-of-hospital cardiac defibrillation: evaluation of AED strategies	95	(16)
Robert J. Myerburg
Shaurtelle Elliot
Donald G. Rosemberg
Alberto Interian Jr.
Agustin Castellanos
Part IV Advances in pacing
David L. Hayes
Sensor and sensor integration	111	(8)
Robert F. Rea
New electrode and lead designs for pacemakers	119	(5)
Charles J. Love
Current concepts in intravascular pacemaker and defibrillator lead extraction	124	(10)
Dhanunjaya R. Lakkireddy
Atul Verma
Bruce L. Wilkoff
Left ventricular epicardial lead implantation: Anatomy, techniques, and tools	134	(11)
Jennifer Cummings
William Belden
Bruce L. Wilkoff
New resynchronization lead systems and devices	145	(9)
Robert F. Rea
New indications for pacing	154	(9)
David L. Hayes
Part V Advances in implantable defibrillators
Paul J. Wang
Implantable defibrillator sensing and discrimination algorithms	163	(15)
Kelly Richardson
Amin Al-Ahmad
Paul J. Wang
Arrhythmia prevention and termination algorithms	178	(9)
Gregory Engel
Paul J. Wang
Amin Al-Ahmad
New lead designs and lead-less systems	187	(10)
Kenneth A. Ellenbogen
Bruce D. Gunderson
Mark A. Wood
Optimization of defibrillation function	197	(9)
Michael R. Gold
Paul J. DeGroot
Remote web-based device monitoring	206	(13)
Edmund Keung
Yang Xue
New ICD indications	219	(14)
Erik Sirulnick
Amin Al-Ahmad
Paul J. Wang
Part VI Advances in catheter surgical ablation
David E. Haines
Advances in surgical ablation devices for atrial fibrillation	233	(9)
Spencer J. Melby
Anson M. Lee
Ralph J. Damiano, Jr.
Epicardial access: present and future applications for interventional electrophysiologists	242	(15)
Robert A. Schweikert
Andre Natale
Advances in catheter control devices	257	(5)
Girish Narayan
Paul J. Wang
Amin Al-Ahmad
Advances in energy sources in catheter ablation	262	(12)
David E. Haines
New ablation paradigms: Anatomic ablation of complex arrhythmia substrates	274	(9)
David J. Callans
Index	283