New Frontiers of Molecular Epidemiology of Infectious Diseases

by Morand, Serge; Beaudeau, Francois; Cabaret, Jacques

• ISBN13: 9789400721135
• ISBN10: 9400721137
• Edition: 1st
• Format: Hardcover
• Copyright: 2011-09-08
• Publisher: Springer Verlag

Summary

Molecular epidemiology has recently broaden its focuses due to the development of molecular tools but also by incorporating advances of other fields such as mathematical epidemiology, molecular ecology, population genetics and evolution. Facing new risks of emerging and re-emerging infectious diseases that are threats for humans and their livestock, the objectives of molecular epidemiology include: - the development of molecular tools, genotyping and gene expression - the incorporation of concepts and results of population genetics of infectious diseases - the integration of recent advances in theoretical epidemiology and evolutionary ecology of diseases - a better understanding of transmission for the development of risk factors analyses. This book will demonstrate how the latest developments in molecular tools and in epidemiology can be integrated with studies of host-pathogen interactions. Besides a strong theoretical component, there will also be an emphasis on applications in the fields of epidemiology, public health, veterinary medicine, and health ecology. Students and researchers in the fields of epidemiology, animal and human health, evolutionary ecology, parasitology are the main potential readers of the book, as well as a broader audience from veterinary medicine and conservation.

Table of Contents

Introduction	p. 1
Methods and Tools in Molecular Epidemiology
Molecular Typing of Bacterial Pathogens: A Tool for the Epidemiological Study and Control of Infectious Diseases	p. 9
Contribution of Population Genetics
Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases	p. 29
Population Genetics and Molecular Epidemiology of Infectious Diseases	p. 45
Contribution of Population and Evolutionary Epidemiology
Modelling the Dynamics of Host-Parasite Interactions: Basic Principles	p. 79
Evolution of Virulence: Intuitions and Models	p. 103
Case Studies
Molecular Epidemiology of Tuberculosis	p. 125
Pneumocystis Molecular Phylogeny: A Way to Understand Both Pneumocystosis Natural History and Host Taxonomy	p. 149
Hantavirus Genetic Diversity	p. 179
New Integrations
Nasal carriage of Methicillin-Resistant Coagulase-Negative Staphylocococci: A Reservoir of mecA Gene for Staphylococcus aureus	p. 219
Molecular Knowledge of Mechanisms of Helminth Resistance: Importance for Diagnostic and Epidemiology	p. 239
Molecular Epidemiology of Disease Resistance Genes with Perspectives for Researches on Biological Invasions and Hybrid Zones	p. 255
How Does Biodiversity Influence the Ecology of Infectious Disease?	p. 291
Epidemiological Interaction at the Wildlife/Livestock/Human Interface: Can We Anticipate Emerging Infectious Diseases in Their Hotspots? A Framework for Understanding Emerging Diseases Processes in Their Hot Spots	p. 311
Conclusion	p. 333
Index	p. 337
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