Nitric Oxide in Pulmonary Processes: Role in Physiology and Pathophysiology of Lung Disease

by Belvisi, Maria G.

• ISBN13: 9783764357184
• ISBN10: 3764357185
• eBook ISBN(s): 9783034884747
• Edition: 1st
• Format: Hardcover
• Copyright: 2000-01-01
• Publisher: BIRKHAUSER BOSTON INC
• More Book Details

Summary

Rhone-Poulenc Rorer, Dagenham, UK. Discusses how NO regulates the physiology and pathophysiology of the lung. Addresses the biochemistry and pharmacology of the different isoforms of nitric oxide synthase (NOS) and synthetic nitro (NO) mimetics. For researchers and clinicians. DNLM: Lung--physiology.

Table of Contents

List of Contributors	vii
Foreword	ix
Introduction to Nitric Oxide Biology
Nitric Oxide Synthesis and Actions	3	(18)
David Bishop-Bailey
Jane A. Mitchell
Reactive Oxygen and Reactive Nitrogen Species in the Lung	21	(20)
Gregroy J. Quinlan
Nicholas J. Lamb
Role of Endogenous Nitric Oxide in the Lung
Non-Adrenergic Non-Cholinergic Neurotransmission in the Airways: Role of Nitric Oxide	41	(30)
Maria G. Belvisi
Alan Gibson
Localisation of Nitric Oxide Synthases in the Lung	71	(18)
Axel Fischer
Role of Nitric Oxide in the Regulation of Pulmonary Vascular Tone	89	(22)
Shu Fang Liu
Timothy W. Evans
Nitric Oxide and Bronchial Hyperresponsiveness	111	(16)
Frans P. Nijkamp
Gert Folkerts
Bronchodilator Actions of Nitric Oxide and Related Compounds	127	(24)
Sanjay Mehta
Jeffrey M. Drazen
Role of Nitric Oxide in Airway Inflammation	151	(16)
El-Bdaoui Haddad
Therapeutic Potential of Inhalded Nitric Oxide and Nitric Oxide Synthase Inhibitors in Lung Disease
Nitric Oxide in Exhaled Air: Relevance in Inflammatory Lung Disease	167	(18)
Peter J. Barnes
Sergei A. Kharitonov
Luminal Nitric Oxide in the Upper Airways: Implications for Local and Distal Sites of Action	185	(16)
Kjell Alving
Jon O.N. Lundberg
Johan Rinder
Eddie Weitzberg
Inhaled Nitric Oxide as a Therapy for Diseases of the Pulmonary Vasculature	201	(8)
Helen M. Marriott
Timothy W. Higenbottam
Combinded Use of Nitric Oxide and Nitric Oxide Synthase Inhibitors as a Possible Therapeutic Approach	209	(18)
Christoph Thiemermann
Index	227