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9781439804797

Nutrition, Epigenetic Mechanisms, and Human Disease

by ;
  • ISBN13:

    9781439804797

  • ISBN10:

    1439804796

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2010-12-03
  • Publisher: CRC Press

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Summary

Extensive research on nutrigenomics has unveiled numerous epigenetic mechanisms that are influenced by our dietary signature. This book illustrates how nutrition can influence epigenetic inheritance and the mechanisms that underlie modification of the metabolic imprint of an individual. The text discusses the basics of nutrigenomics and epigenetic regulation, types of nutrition influencing genetic imprinting, and the role of nutrition in modulating an individual's predisposition to disease. It also covers epigenetic variation, genomic imprinting, maternal nutrition, neonatal nutrition, as well as epigenetics and nutrition relating to cancer, heart disease, and obesity.

Table of Contents

Prefacep. ix
Acknowledgmentsp. xi
The Editorsp. xiii
Contributorsp. xv
Nutritional Epigenetics and Disease Prevention: Are We There Yet?p. 1
Aging by Epigenetics: Nutrition, An Epigenetic Key to Long Lifep. 13
Folate and DNA Methylationp. 31
Dietary Components, Epigenetics, and Cancerp. 77
Dietary Factors, Histone Modifications, and Cancer Preventionp. 109
Nutrition, Epigenetics, and Vascular Functionp. 125
Role of Epigenetic Machinery and MicRNAs in Diet-Induced Hepatocarcinogenesisp. 141
Epigenetic Mechanisms in Lung Inflammation and Chronic Airway Diseases and Intervention by Dietary Polyphenolsp. 185
Glycemic Memory and Epigenetic Changesp. 215
Maternal Nutrition, Intrauterine Development, and Disease Risks in the Offspring through Epigenetic Regulation of Gene Expressionp. 229
Nutritional Epigenetics: Impact on Metabolic Syndromep. 259
Nutrition and the Emerging Epigenetic Paradigm: Lessons from Neurobehavioral Disordersp. 287
Interactions between Folate, Other B Vitamins, DNA Methylation, and Neurodevelopmental Disordersp. 317
Dietary Factors and the Emerging Role of Epigenetics in Neurodegenerative Diseasesp. 363
Indexp. 381
Table of Contents provided by Ingram. All Rights Reserved.

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