Obesity and Diabetes

by Mantzoros, Christos S., M.D.

• ISBN13: 9781588295385
• ISBN10: 1588295389
• Format: Hardcover
• Copyright: 2006-02-15
• Publisher: Humana Pr Inc

Summary

International experts from world-renowned medical schools comprehensively review for practicing clinicians and scientists alike the latest understanding of the epidemiology, causation, and consequences of diabetes and obesity. The authors discuss in detail their diagnosis, clinical manifestations, complications, and best practices for diagnosis and treatment. They also review the history and epidemiology of these conditions, explain their genetics and pathophysiology, and illuminate their known mechanisms and interactions. State-of-the-art survey-chapters critique current approaches (lifestyle and pharmacological) to the treatment of these conditions.

Table of Contents

Dedication	v
Series Editor's Introduction	vii
Preface	ix
Contributors	xv
Part I History and Epidemiology
Obesity and Diabetes: The Historical Events Marking the Evolution of the Understanding of the Pathophysiology and Treatment of Two Related Diseases	3	(12)
George Karanastasis
Christos S. Mantzoros
Epidemiology of Obesity and Diabetes: Prevalence and Trends	15	(24)
Susanna C. Larsson
Alicja Wolk
Part II Genetics and Pathophysiology
Genetics of Obesity and Diabetes	39	(30)
Despina Sanoudou
Christos S. Mantzoros
Nutrients and Peripherally Secreted Molecules in Regulation of Energy Homeostasis	69	(18)
Greeshma K. Shetty
Diana Barb
Christos S. Mantzoros
Central Integration of Peripheral Signals in Regulation of Energy Homeostasis	87	(12)
Greeshma K. Shetty
George Karanastasis
Christos S. Mantzoros
Role of Energy Expenditure in Regulation of Energy Homeostasis	99	(18)
Eric S. Bachman
Pathophysiology of Diabetes in Obesity	117	(12)
Geetha R. Soodini
Osama Hamdy
Part III Diagnosis, Clinical Manifestations, and Complications
Diagnosing Obesity, Diabetes Mellitus, and the Insulin Resistance Syndrome	129	(26)
Diana Barb
Christos S. Mantzoros
Metabolic Syndrome	155	(14)
Rochelle L. Chaiken
Mary Ann Banerji
Obesity, Diabetes, and Hypertension	169	(24)
Anjanette S. Tan
Stephen A. Brietzke
David W. Gardner
James R. Sowers
Dyslipidemia Associated With Diabetes and Insulin Resistance Syndromes	193	(20)
Jody Dushay
J. Peter Oettgen
Obesity, Diabetes, and Endothelial Dysfunction	213	(8)
Geetha R. Soodini
Edward S. Horton
Osama Hamdy
Atherosclerosis and Peripheral Vascular Disease: Sequelae of Obesity and Diabetes	221	(12)
Satish N. Nadig
Allen Hamdan
Obesity, Diabetes, and Risk of Cancer: A Review of Epidemiological Studies	233	(22)
Susanna C. Larsson
Hans-Olov Adami
Alicja Wolk
Polycystic Ovary Syndrome and Its Metabolic Complications	255	(22)
Emilia P. Liao
Leonid Poretsky
Obesity and Type 2 Diabetes Mellitus in Childhood and Adolescence	277	(14)
Susann Bluher
Wieland Kiess
Diabetic Retinopathy	291	(28)
Vassiliki Poulaki
Joan W. Miller
Obesity and Renal Disease	319	(14)
Ayman Geneidy
Richard Solomon
Diabetic Peripheral Neuropathy	333	(18)
Rachel Nardin
Roy Freeman
The Diabetic Foot	351	(12)
Thanh L. Dinh
Aristidis Veves
Erectile Dysfunction	363	(14)
Kenneth J. Snow
Infections in Diabetes Mellitus	377	(26)
Sotirios Tsiodras
Iosif Kelesidis
Christos S. Mantzoros
Adolf W. Karchmer
The HAART-Induced Metabolic Syndrome	403	(26)
Sotirios Tsiodras
Theodoros Kelesidis
Christos S. Mantzoros
Part IV Treatment
Diet and Lifestyle in the Prevention and Management of Type 2 Diabetes	429	(16)
Frank B. Hu
Diet, Exercise, and Behavioral Treatment of Obesity	445	(12)
George L. Blackburn
Medical Approaches to Treatment of the Obese Patient	457	(14)
George A. Bray
Donna H. Ryan
Medical Treatment of the Obese Patient With Type 2 Diabetes	471	(16)
Jean L. Chan
Christos S. Mantzoros
Martin J. Abrahamson
Surgical Treatment of Obesity and Diabetes	487	(10)
Benjamin E. Schneider
Edward C. Mun
Future Developments in the Area of Pharmacotherapy: Molecules in Early-Stage Preclinical Development and in Clinical Trials That May Affect Energy Homeostasis	497	(16)
Diana Barb
Greeshma K. Shetty
Christos S. Mantzoros
Appendix: Resources	513	(12)
Violeta Stoyneva
Christos S. Mantzoros
Index	525