Obstructive Sleep Apnea: Pathophysiology, Comorbidities and Consequences: Pathophysiology, Comorbidities, and Consequences

by Kushida; Clete A.

• ISBN13: 9780849391804
• ISBN10: 0849391806
• Edition: 1st
• Format: Hardcover
• Copyright: 2007-05-17
• Publisher: CRC Press

Summary

Responding to the growing recognition of Obstructive Sleep Apnea (OSA) as a major medical condition and the emergence of exciting new therapies, this source analyzes the clinical features, characteristics, comorbidities, and impact of OSA on patient biological systems and quality-of-life. Edited by the Director of the Center for Human Sleep Research at Stanford, this source supplies an all-encompassing guide to the comorbid medical conditions and socioeconomic impact of OSA.

Table of Contents

Preface	p. iii
Contributors	p. vii
Perspectives	p. 1
Features, Factors, and Characteristics
History	p. 11
Epidemiology	p. 27
Ontogeny	p. 39
Phylogeny and Animal Models: An Uninhibited Survey	p. 61
Upper Airway Anatomy	p. 81
Physiology and Dynamics of the Upper Airway	p. 93
Upper Airway Pathology	p. 111
Control of Breathing in Sleep	p. 125
Arousal from Sleep	p. 149
Pathogenesis	p. 171
Risk Factors	p. 197
Familial and Genetic Factors	p. 223
The Spectrum of Sleep-Disordered Breathing	p. 245
Associations and Consequences
Morbidity and Mortality	p. 259
Central and Autonomic Nervous Systems	p. 275
Cardiac Arrhythmias and Congestive Heart Failure	p. 293
Hypertension and the Cardiovascular System	p. 323
Endocrine Function and Glucose Metabolism	p. 337
Obesity	p. 355
Mood and Behavior	p. 377
Sleepiness	p. 393
Health-Related Quality-of-Life	p. 425
Driving Risk and Accidents	p. 443
Economic and Societal Impact	p. 451
Index	p. 473
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