Organ Transplantation

by Editor: Leo C. Ginns; Editor: A. Benedict Cosimi; Editor: Peter J. Morris

• ISBN13: 9780865425200
• ISBN10: 0865425205
• Edition: Illus.
• Format: Hardcover
• Copyright: 1999-06-01
• Publisher: Wiley-Blackwell

Summary

Transplantation is the first comprehensive, single-volume reference devoted to organ and tissue transplantation. Edited by three outstanding clinicians with contributions from over fifty international experts this exciting new book covers all dimensions of the transpantation process, from basic immunology and immunosuppresssion, through donor management and inividual organ transplant techniques and complications. Special brief commentaries offer colourful editorial comments on many selected chapters, providing multidimensional views of a given issue. For all those involved in the medical and surgical aspects of organ transplants, Transplantation serves as the most current, complete an authoritative resource available.

Table of Contents

Contributors	xi
Foreword	xvii
Paul S. Russell
Preface	xxi
Reaching for the Impossible: The Quest for Tissue Replacement	1	(22)
David Hamilton
PART I Immunology
Immunobiology of Graft Rejection	23	(20)
Margaret J. Dallman
Commentary	36	(7)
Leendert C. Paul
Chronic Rejection	43	(17)
Nicholas L. Tilney
Commentary	53	(7)
Pekka Hayry
Histocompatibility Systems	60	(19)
Charles B. Carpenter
Commentary	74	(5)
Ken Welsh
Tolerance	79	(22)
Megan Sykes
David H. Sachs
Commentary	93	(8)
Kathryn J. Wood
PART II Immunosuppression
Molecular and Clinical Therapeutics of Cyclosporine in Transplantation	101	(12)
Paul A. Keown
Azathioprine	113	(2)
Roy Y. Calne
Steroids and Transplantation	115	(12)
Rowan G. Walker
Commentary	123	(4)
Henri Kreis
Tacrolimus	127	(20)
Goran B. Klintmalm
Commentary	136	(11)
Thomas E. Starzl
John J. Fung
Mycophenolate Mofetil: Experimental and Clinical Experience	147	(20)
Stephen C. Rayhill
Hans W. Sollinger
Commentary	162	(5)
Carl G. Groth
Christina Brattstrom
New Small Molecule Immunosuppressive Agents	167	(18)
Ferda Senel
Barry D. Kahan
Commentary	179	(6)
Karl Wagner
Principles of Action of Biologic Immunosuppressants	185	(11)
Lucienne Chatenoud
Biologic Immunosuppressive Agents	196	(21)
James D. Eason
A. Benedict Cosimi
Commentary	217	(4)
Jean-Paul Soulillou
Use of Irradiation and Photopheresis for Immunosuppression in Transplantation	221	(10)
Mark Waer
Commentary	231	(8)
J. A. Myburgh
PART III Organ Procurement
Donor Selection and Management	239	(32)
Kevin J. O'Connor
Francis L. Delmonico
Commentary	265	(6)
Gauke Kootstra
Organ Preservation	271	(14)
James H. Southard
Mary S. Ametani
Commentary	279	(6)
David Pegg
PART IV Organ-Specific Transplantation
Renal Transplantation	285	(27)
Peter J. Morris
Commentary by Kazuo Ota	307	(5)
Renal Transplantation in Children: Current Practices	312	(12)
Richard N. Fine
Commentary	321	(3)
Michel Broyer
Liver Transplantation	324	(50)
John A. Powelson
A. Benedict Cosimi
Commentary	366	(8)
Paul McMaster
Liver Transplantation in Children	374	(21)
Sue V. McDiarmid
Pancreas Transplantation	395	(27)
Hugh Auchincloss
David Shaffer
Commentary	413	(9)
David E. R. Sutherland
Intestinal and Multivisceral Transplantation	422	(16)
Farrukh A. Khan
Andreas G. Tzakis
Commentary by David Grant	434	(4)
Cardiac Transplantation	438	(36)
G. William Dec
Commentary by Dale G. Renlund	468	(6)
Heart Transplantation in Children	474	(16)
Luca A. Vricella
Leonard L. Bailey
Commentary	485	(5)
Lori J. West
Lung Transplantation	490	(61)
Leo C. Ginns
John C. Wain
Heart-Lung Transplantation	551	(9)
George V. Letsou
John C. Baldwin
Bone Marrow Transplantation	560	(31)
Thomas R. Spitzer
Steven L. McAfee
Commentary	582	(9)
John M. Goldman
PART V Systemic Considerations of Organ Transplantation
Pulmonary Considerations of Organ Transplantation	591	(37)
Sanjiv Tewari
Janet Maurer
Gastroenterologic Considerations of Organ Transplantation	628	(23)
Philip L. Shields
James M. Neuberger
Cardiovascular Considerations of Organ Transplantation	651	(21)
Marc J. Semigran
Endocrine and Metabolic Considerations of Organ Transplantation	672	(13)
Maria A. Rodino
Neil Shachter
Elizabeth Shane
Hematologic Considerations of Organ Transplantation	685	(11)
Johan F. Vanwalleghem
Yves F. Ch. Vanrenterghem
Neurologic Considerations of Organ Transplantation	696	(13)
Michael Donaghy
Psychiatric Considerations of Organ Transplantation	709	(16)
Owen S. Surman
Renal Considerations of Organ Transplantation	725	(22)
Nina Tolkoff-Rubin
Erik Langhoff
Infection in the Organ Transplant Recipient	747	(23)
Robert H. Rubin
Jay A. Fishman
Neoplastic Complications of Organ Transplantation	770	(19)
Israel Penn
Commentary	783	(6)
Darlene S. Johnson
Jessica L. Fewkes
Arthur J. Sober
PART VI The Future of Transplantation
Bone Marrow Conditioning	789	(25)
Douglas A. Hale
Anthony P. Monaco
Commentary	809	(5)
Haval Shirwan
Suzanne T. Ildstad
Gene Transfer	814	(13)
Kathryn J. Wood
Commentary	823	(4)
Stuart J. Knechtle
Xenotransplantation	827	(48)
Ian F. C. McKenzie
Bruce E. Loveland
Jay A. Fishman
Hugh Auchincloss
Mauro S. Sandrin
Commentary	866	(9)
David K. C. Cooper
Understanding Organ Procurement and the Transplant Bureaucracy	875	(22)
James F. Burdick
Johan DeMeester
Isamu Koyama
Commentary	894	(3)
Jeremy Chapman
Transplantation and Society	897	(17)
A. G. R. Sheil
Commentary	911	(3)
Ronald D. Guttmann
Index	914