Osteoarthritis Diagnosis and Medical/Surgical Management

by Moskowitz, Roland W.; Altman, Roy D.; Buckwalter, Joseph A.; Goldberg, Victor M.; Hochberg, Marc C.

• ISBN13: 9780781767071
• ISBN10: 0781767075
• Edition: 4th
• Format: Hardcover
• Copyright: 2006-12-05
• Publisher: LWW

Summary

Written by the foremost experts, this text is a comprehensive clinical reference on osteoarthritis. Chapters review current information on the epidemiology, etiopathogenesis, and pathology of osteoarthritis, the biochemistry and molecular and cell biology of articular cartilage, and experimental models of osteoarthritis. Major sections focus on clinical presentations, roentgenologic and laboratory diagnosis, and treatment, including pharmacologic treatment, intra-articular therapy, surgery, arthroscopy, and complementary and alternative medicine. The authors discuss the indications, outcomes, and complications of various orthopaedic procedures. Chapters present orthopaedic approaches to osteoarthritis of various joints--the shoulder, hand, wrist, elbow, hip, knee, foot, ankle, and cervical, thoracic, and lumbar spine.

Table of Contents

Foreword	p. vii
Preface	p. ix
Contributors	p. xi
Acknowledgments	p. xv
Basic Considerations	p. 1
Epidemiology of Osteoarthritis	p. 3
Etiopathogenesis of Osteoarthritis	p. 27
Pathology of Osteoarthritis	p. 51
Cell Biology, Biochemistry, and Molecular Biology of Articular Cartilage in Osteoarthritis	p. 73
Experimental Models of Osteoarthritis	p. 107
Molecular Genetics of Osteoarthritis	p. 127
General Aspects of Diagnosis	p. 137
Osteoarthritis: Clinical Presentations	p. 139
Radiologic Diagnosis	p. 147
Magnetic Resonance Imaging	p. 167
Ultrasound and Alternative Imaging Outcomes	p. 193
Laboratory Findings in Osteoarthritis	p. 201
Noninvasive Biochemical Markers in Osteoarthritis	p. 215
Secondary Osteoarthritis	p. 233
General Aspects of Management	p. 255
Baseline Program	p. 257
The Pharmacologic Treatment of Osteoarthritis	p. 267
Intra-Articular Therapy	p. 287
Complementary and Alternative Medicine	p. 303
Study Design and Outcome Measures in Osteoarthritis Clinical Trials	p. 313
Surgical Considerations in Osteoarthritis	p. 327
General Considerations, Indications, and Outcomes	p. 329
Upper Extremity Considerations: Osteoarthritis of the Shoulder	p. 339
Upper Extremity Considerations: Hand, Wrist, and Elbow	p. 349
Lower Extremity Considerations: Hip	p. 375
Lower Extremity Considerations: Knee	p. 395
Lower Extremity Considerations: Foot and Ankle	p. 415
Osteoarthritis of the Spine	p. 427
New Frontiers in Surgery of Osteoarthritis	p. 453
Index	p. 461
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