Outcomes Assessment in Cancer

by Lipscomb, Joseph; Gotay, Carolyn C.; Snyder, Claire

• ISBN13: 9781107403161
• ISBN10: 1107403162
• Edition: Revised
• Format: Paperback
• Copyright: 2011-08-18
• Publisher: Cambridge Univ Pr

Summary

Cancer touches the lives of millions worldwide each year. This is reflected not only in well-publicized mortality statistics but also in the profound - though much more difficult to measure - effects of cancer on the health-related quality of life, economic status, and overall well-being of patients and their families. In 2001, the US National Cancer Institute established the Cancer Outcomes Measurement Working Group to evaluate the state of the science in measuring the important and diverse impacts of this disease on individuals and populations. The findings and recommendations of the working group's 35 internationally recognized members are reported in Outcomes Assessment in Cancer, lucidly written and accessible to both researchers and policy makers in academia, government, and industry. Originally published in 2005, this volume provides a penetrating yet practical discussion of alternative approaches for comprehensively measuring the burden of cancer and the effectiveness of preventive and therapeutic interventions.

Table of Contents

Acknowledgments

Introduction

Definitions and conceptual models of quality of life

Assessing health status and quality of life of cancer patients: the use of general instruments

The roles for preference-based measures in support of cancer research and policy

Instruments to measure the specific health impact of surgery, radiation and chemotherapy on cancer patients

Quality of life in breast cancer - what have we learned and where do we go from here?

Measuring quality of life in prostate cancer: progress and challenges

The science of quality of life measurement in lung cancer

Treatment for colorectal cancer: impact on health-related quality of life

Short-term outcomes of chemoprevention, genetic susceptibility testing and screening interventions: what are they? How are they measured? When should they be measured?

Evaluating quality of life in cancer survivors

Assessing health-related quality of life at end of life

Patient advocate perspective on health-related quality of life issues with prostate cancer survivors

Measuring the patient's perspective on the interpersonal aspects of cancer care

Needs assessment in cancer

Assessing the subjective impact of caregiving on informal caregivers of cancer patients

Practical considerations in outcomes assessment for clinical trials

Statistical issues in the application of cancer outcome measures

The clinical value and meaning of health-related quality-of-life outcomes in oncology

Cross-cultural use of health-related quality of life assessments in clinical oncology

Item response theory and its applications for cancer outcomes measurement

Applications of item response theory to improve health outcomes assessment: developing item banks, linking instruments, and computer-adaptive testing

Subscales and summary scales: issues in health-related outcomes

On the definition and measurement of the economic burden of cancer

Cost-effectiveness analysis in cancer: toward an iterative framework for integration of evidence from trials and models

Data for cancer outcomes research: identifying and strengthening the empirical base

Use of health-related quality-of-life measures by industry and regulatory agencies in evaluating oncology therapies

Reflections on COMWG findings and moving to the next phase

Invited Papers

The world of outcomes research: yesterday, today, and tomorrow

The ten D's of health outcomes measurement for the 21st Century

The use of cognitive interviewing techniques in quality of life and patient-reported outcomes assessment

Industry perspective regarding outcomes research in oncology

Index

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