Oxford Handbook of Rheumatology

At last, a unique practical pocket guide emphasizing the clinical evidence-based approach to Rheumatology. Rheumatic conditions are common both in general and hospital practice and the breadth and complexity of rheumatic conditions that general practitioners and specialists encounter is quite astounding. Developing history-taking and clinical examination skills is fundamental to making a diagnosis andsuccessful long-term monitoring of rheumatic conditions. The Oxford Handbook of Rheumatology is a practical, clinical guide to the diagnosis and management of rheumatic disorders.Section 1 takes the reader through common patterns of disease presentation and encourages the reader to consider differential diagnosis and then to refer to Section 2. Section 1 also contains some aspects of the general management of rheumatic diseases, particularly the principles of painassessment, soft tissue and joint injections, and phsyiotherapy.Section 2 is a more formal and traditional review of the common rheumatic disorders. Each subsection introduces important diagnostic and therapeutic detail without burdening the reader with fundamental basic science. The second section has been written with an international audience in mind,incorporating UK, European, and US disease criteria where possible. The Oxford Handbook of Rheumatology highlights childhood and adolescent rheumatic disease throughout and is written in conjunction with the celebrated major reference work, the Oxford Textbook of Rheumatology.Editorial advisors:Professor Peter MaddisonProfessor David IsenbergProfessor Pat WooProfessor David Glass

Part 1: The presentation of rheumatic disease

1

(251)

Evaluating musculoskeletal pain

3

(10)

Introduction

4

(2)

Localization of pain and pain patterns

6

(2)

Eliciting changes in pain by the use of examination techniques

8

(2)

The assessment of pain in young children

10

(3)

Regional musculoskeletal conditions: making a working diagnosis

13

(154)

Introduction

14

(2)

Neck pain

16

(9)

Shoulder pain

25

(13)

Pain around the elbow

38

(8)

Wrist pain

46

(6)

Symptoms in the hand

52

(12)

Upper limb peripheral nerve lesions

64

(6)

Thoracic back and chest pain

70

(8)

Low back pain and disorders in adults

78

(16)

Spinal disorders in children and adolescents

94

(8)

Pelvic, groin, and thigh pain

102

(14)

Knee pain

116

(16)

Lower leg and foot disorders (adults)

132

(14)

Child and adolescent foot disorders

146

(12)

Corticosteroid injection therapy

158

(6)

Principles of rehabilitation

164

(3)

Patterns of disease presentation: making a working diagnosis

167

(66)

Oligoarticular pains in adults

168

(12)

Oligoarticular pains in children and adolescents

180

(10)

Widespread pain in adults

190

(20)

Widespread pain in children and adolescents

210

(10)

Skin disorders and rheumatic disease

220

(6)

Skin vasculitis in adults

226

(4)

Skin vasculitis in children and adolescents

230

(3)

The spectrum of presentation of rheumatic disease

233

(18)

Endocrine conditions

234

(6)

Gut and hepatobiliary conditions

240

(6)

Malignancy

246

(5)

Part 2: The clinical features and management of rheumatic diseases

251

(300)

Rheumatoid arthritis

253

(24)

Disease criteria and epidemiology

254

(2)

Incidence, prevalence and morbidity

256

(2)

The clinical features of rheumatoid arthritis

258

(2)

Organ disease in rheumatoid arthritis

260

(4)

The evaluation and treatment of rheumatoid arthritis

264

(12)

Rheumatoid factor positive polyarthritis in childhood

276

(1)

Osteoarthritis (OA)

277

(12)

Introduction

278

(2)

Clinical features of OA

280

(4)

The investigation of OA

284

(2)

The management of OA

286

(3)

Juvenile idiopathic arthritis (JIA)

289

(24)

Introduction

290

(2)

Oligoarticular JIA

292

(6)

Systemic onset JIA

298

(6)

Adult-onset Still's disease

304

(2)

Rheumatoid factor negative JIA

306

(4)

Chronic infantile neurological cutaneous and articular syndrome

310

(3)

The spondylarthropathies

313

(24)

Introduction

314

(2)

Diagnostic criteria and clinical subsets

316

(4)

Ankylosing spondylitis

320

(6)

Psoriatic arthritis

326

(2)

Reactive arthropathy (Reiter's syndrome)

328

(4)

Enteric arthropathy

332

(2)

Spondylarthropathies in childhood

334

(3)

Systemic lupus erythematosus (SLE)

337

(24)

Introduction

338

(2)

The clinical features of SLE

340

(6)

Antiphospholipid (antibody) syndrome and SLE

346

(2)

Pregnancy and SLE

348

(2)

Assessment and investigation of SLE

350

(4)

Drug-induced lupus

354

(2)

The treatment of SLE

356

(2)

Prognosis and survival in SLE

358

(2)

Childhood SLE

360

(1)

The antiphospholipid (antibody) syndrome

361

(8)

Introduction

362

(2)

Clinical features of APS

364

(2)

Treatment of antiphospholipid syndrome

366

(3)

Sjogren's syndrome

369

(10)

Introduction

370

(2)

Clinical manifestations of Sjogren's syndrome

372

(4)

The investigation of Sjogren's syndrome

376

(2)

Treatment of Sjogren's syndrome

378

(1)

Scleroderma and related disorders

379

(22)

Introduction

380

(4)

The cutaneous features of scleroderma and their treatment

384

(4)

The systemic features of the disease, investigation and treatment

388

(6)

Antifibrotic and immunosuppressive therapies for systemic sclerosis

394

(2)

Summary--the approach to systemic sclerosis

396

(2)

Eosinophilia-myalgia syndrome

398

(2)

Eosinophilic fasciitis

400

(1)

Polymyositis (PM) and dermatomyositis (DM)

401

(20)

Introduction

402

(2)

Clinical features of PM and DM

404

(4)

Investigation of PM and DM

408

(6)

Treatment of PM and DM

414

(2)

Inclusion-body myositis

416

(2)

PM and DM in children

418

(3)

Primary vasculitides

421

(30)

Introduction

422

(4)

Large vessel vasculitis

426

(2)

Takayasu's arteritis

428

(2)

Polymyalgia rheumatica and giant cell arteritis

430

(4)

Wegener's granulomatosis

434

(6)

Classical polyarteritis nodosa, microscopic polyangiitis and Churg-Strauss syndrome

440

(6)

Small vessel vasculitis

446

(5)

The crystal arthropathies

451

(14)

Gout and hyperuricaemia

452

(6)

Calcium pyrophosphate dihydrate (CPPD) disease

458

(4)

Basic calcium phosphate (BCP) associated disease

462

(2)

Calcium oxalate arthritis

464

(1)

Metabolic bone diseases

465

(40)

Osteoporosis

466

(12)

Osteomalacia and rickets

478

(6)

Parathyroid disease and related disorders

484

(8)

Paget's disease of bone

492

(4)

Miscellaneous diseases of bone and collagen in adults and children

496

(9)

Infection and inflammatory rheumatic disease

505

(16)

Introduction

506

(4)

Pyogenic non-gonococcal and gonococcal arthritides

510

(3)

Tuberculosis

513

(1)

Osteomyelitis

514

(2)

Lyme disease

516

(2)

Rheumatic fever

518

(3)

Miscellaneous conditions

521

(30)

Behcet's syndrome

522

(4)

Sarcoidosis

526

(4)

Miscellaneous skin conditions associated with arthritis

530

(6)

Algodystrophy (reflex sympathetic dystrophy syndrome)

536

(4)

Relapsing polychondritis

540

(2)

Miscellaneous disorders of synovium

542

(2)

Amyloidosis

544

(4)

Fibromyalgia

548

(3)

Appendix: Useful contacts

551

(2)

Index

553

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