The Pancreas An Integrated Textbook of Basic Science, Medicine, and Surgery

by Beger, Hans-Gunther; Buchler, Markus; Kozarek, Richard; Lerch, Markus; Neoptolemos, John; Warshaw, Andrew; Whitcomb, David; Shiratori, Keiko

• ISBN13: 9781405146647
• ISBN10: 1405146648
• Edition: 2nd
• Format: Hardcover
• Copyright: 2008-05-12
• Publisher: Wiley-Blackwell

Summary

The encyclopedic guide to the pancreas for practicing clinicians and surgeonsIn the past decade extraordinary developments in diagnostic and therapeutic radiology and endoscopy have been coupled with major advances in surgical techniques and basic sciences. As a result the management of pancreatic disorders is now handled by a multidisciplinary team. This book shows you how to achieve superior patient management by taking the team approach to in-hospital care.Fully revised and updated, this new edition of The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery details the latest knowledge on genetics and molecular biological background in terms of anatomy, physiology, pathology, and pathophysiology for all known pancreatic disorders. The Editor and author team are leading pancreatologists of high international repute and they present global best-practice and evidence-based knowledge in this comprehensive reference.A timely section on early and late outcome data considers the benefits of management including chemotherapy and immune therapy. Incorporating evidence-based data, the book also focuses on early diagnosis, limited surgical treatment, oncology, treatment results and the option of transplantation.This new edition contains more than 400 illustrations, line drawings and radiographs to provide a step-by-step approach to endoscopic techniques and surgical procedures. With The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery, Second Edition, you can achieve a greater understanding of current diagnostic, medical and surgical treatment principles in one authoritative reference point.

Author Biography

Professor Hans Beger MD FACS is Chairman and Head of the Department of Surgery, University of Ulm, Germany. He has published 675 papers and has served as an Editorial Board Member for 28 international surgery journals. He has also edited 21 books and delivered more than 250 international lectures. He also developed a surgical procedure for removing the head of the pancreas while preserving the duodenum: known as Beger's operation.


Professor Andrew L. Warshaw MD FACS is the W. Gerald Austen Professor of Surgery, surgeon-in-chief and chairman of the Department of Surgery at Massachusetts General Hospital. He has made important contributions to the diagnosis and treatment of pancreatic cancer and the pathogenesis and management of pancreatitis. A distinguished teacher, editor and prolific writer, he is Editor-in-chief of the journal Surgery. He has served on the editorial boards of 15 other major journals and as visiting professor at more than 50 major universities in the U.S. and around the world. He serves as a governor of the American College of Surgeons, and president-elect of the Halsted Society. He is past-president of the Society of Surgery of the Alimentary Tract and International Association of Pancreatology.


Professor David Whitcomb MD PhD, is Professor of Medicine, Cell Biology & Physiology, and Human Genetics, and Chief, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh, PA, USA (Pancreatologist). He founded and directs the Center for Genomic Sciences beginning in 1995. He has received numerous awards, including election to the prestigious American Society for Clinical Investigation ("Young Turk"). He conducts basic and translational research with a focus on pancreatic diseases. His laboratory group discovered the gene causing hereditary pancreatitis and other causes of pancreatic disease. In addition, he leads several research projects on alcoholic pancreatitis and pancreatic physiology. He has published over 100 manuscripts and recently co-edited two books on inherited diseases of the pancreas. He is a Counselor for the American Gastroenterology Association (AGA), the American Pancreas Association and the International Association of Pancreatology, and is Chairman of the Pancreatic Disorders Section of the AGA. He is an Associate Editor for Pancreas, Digestive Diseases and Sciences, and Pancreatology. He co-founded the Midwest Multicenter Pancreatic Study Group and serves on national and international committees for the major gastroenterology and pancreatic societies. He has just been elected President of the American Pancreas Association.


Professor Richard Kozarek, Chief of Gastroenterology, Virginia Mason Medical Center, and Clinical Professor of Medicine, University of Washington, Seattle, Washington

Table of Contents

Contributors

Preface

Definitions of pancreatic diseases and their complications

Anatomy of the pancreas

The history of the pancreas

Development of the pancreas and related structures

Anatomy and fine structure

Congenital and inherited anomalies

Physiology of pancreatic functions

Physiology of acinar cell secretion

Physiology of duct cell secretion

Physiology of experimental pancreatitis

Physiology of sphincter of Oddi function

Neurohormonal and hormonal control of exocrine pancreatic secretion

Regulation of pancreatic protein synthesis and growth

Insulo-acinar relationship

Acute pancreatitis

Etiopathogenesis and epidemiology of alcohol-induced acute pancreatitis

Etiology and epidemiology of biliary acute pancreatitis

Acute pancreatitis associated with congenital anomalies

Acute pancreatitis associated with metabolic, infectious, and drug-related diseases

Acute pancreatitis in children

Understanding of acute pancreatitis from animal experiments

Genetic factors in acute pancreatitis

Histopathology of acute pancreatitis

Molecular, biochemical, and metabolic abnormalities of acute pancreatitis

Clinical course of alcoholic acute pancreatitis

Clinical course and treatment principles of biliary acute pancreatitis

Clinical assessment and biochemical markers to objectify severity and prognosis

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