The Pathogenic Enteric Protozoa

by Sterling, Charles R.; Adam, Rodney D.

• ISBN13: 9781402077944
• ISBN10: 1402077947
• Format: Hardcover
• Copyright: 2004-03-01
• Publisher: Kluwer Academic Pub

Summary

The Pathogenic Enteric Protozoa: Giardia, Entamoeba, Cryptosporidium and Cyclospora compromise the health of millions of people, largely from developing nations. These protozoan parasitic agents contribute significantly to the staggering caseload of diarrheal disease morbidity encountered in developing world nations. Compounding the issue of their mere presence is the fact that standard ova and parasite exams frequently do not detect these infections. Detectable stages may be shed intermittently or require specialized staining procedures. Added to this is the often large number of asymptomatic carriers who serve as reservoirs for infecting others. These parasites are also not strangers to more developed nations, having responsibility for both small and large-scale disease outbreaks. In such settings they may be even more difficult to detect simply because they are frequently overlooked in the grand scheme of disease causing possibilities. They share common features: all are Protozoa, all possess trophic stages that inhabit the gastrointestinal tract, all have the ability to produce disease and in some instances death, and all produce environmentally stable cysts or oocysts, which ensure their transmissibility.

Author Biography

Charles R. Sterling is a Professor in the Department of Veterinary Science and Microbiology at the University of Arizona, Tucson, Arizona.Rodney D. Adam is a Professor in the Department of Microbiology and Immunology at the University Of Arizona Health Science Center, Tucson, Arizona.

Table of Contents

List of contributors
Preface
Epidemiology and zoonotic potential of Giardia infections	p. 1
Entamoeba histolytica and Entamoeba dispar, the non-identical twins	p. 15
Epidemiology and strain variation of Cryptosporidium	p. 27
Cyclospora cayetanensis : an emergent and still perplexing coccidian parasite	p. 43
Antigenic variation of the VSP genes of Giardia lamblia	p. 59
Pathogenesis and immunity to Entamoeba histolytica	p. 75
Innate and T cell-mediated immune responses in cryptosporidiosis	p. 91
Rationale approaches to treating Cryptosporidium, Cyclospora, Giardia and Entamoeba	p. 103
Inactivation and removal of enteric protozoa in water	p. 117
Monitoring of Giardia and Cryptosporidium in water in the UK and US	p. 129
Entamoeba histolytica genome	p. 141
Cryptosporidium parvum genomics : impact on research and control	p. 153
Index	p. 615
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