Pathology and Clinical Relevance of Neoplastic Precursor Lesions of the Gastrointestinal Tract, Liver, and Pancreaticobiliary System

by Odze, Robert D.

• ISBN13: 9781416050735
• ISBN10: 1416050736
• Edition: 1st
• Format: Hardcover
• Copyright: 2007-12-13
• Publisher: Elsevier Science Health Science div

Summary

Due to recent advances in endoscopy and radiology, there is increased recognition of the prevalence and biological characteristics of neoplastic precursor lesions in the GI tract, liver, biliary tract, and pancreas. As a result, there have been major recent developments in the pathologic classification, diagnosis, molecular pathogenesis, natural history and treatment of these lesions. In addition, there are controversial issues with regard to the value of endoscopic screening and surveillance. A close clinician-pathologist interaction is essential in the management of preneoplastic lesions. In this issue the pathology, biological properties, pathogenesis, natural history, and current treatment recommendations of the major preneoplastic and dysplastic precursor lesions of the GI tract, liver, biliary tract and pancreas are reviewed in detail. Wherever possible, accent is given to controversial diagnostic and management-related issues. Each subject matter is written by experts in the field, all of whom have had research experience in their respective areas.

Table of Contents

Preface	p. xi
Neoplastic Precursor Lesions in Barrett's Esophagus	p. 775
Squamous Dysplasia and Other Precursor Lesions related to Esophageal Squamous Cell Carcinoma	p. 797
Gastric Preneoplastic Lesions and Epithelial Dysplasia	p. 813
Precursors to Pancreatic Cancer	p. 831
Endocrine Hyperplasia and Dysplasia in the Pathogenesis of Gastrointestinal and Pancreatic Endocrine Tumors	p. 851
Hepatic Precancerous Lesions and Small Hepatocellular Carcinoma	p. 867
Neoplastic Precursors of the Gallbladder and Extrahepatic Biliary System	p. 889
Neoplastic Precursor Lesions Related to the Development of Cancer in Inflammatory Bowel Disease	p. 901
Gastrointestinal Polyposes: Clinical Pathological and Molecular Features	p. 927
Hyperplastic and Serrated Polyps of the Colorectum	p. 947
Anal Intraepithelial Neoplasia and Other Neoplastic Precursor Lesions of the Anal Canal and Perianal Region	p. 969
Index	p. 989
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