Pathology and Therapeutics for Pharmacists

by Greene, Russell J.; Harris, Norman D.; Goodyer, Larry I. (CON)

• ISBN13: 9780853693734
• ISBN10: 0853693730
• Edition: 2nd
• Format: Paperback
• Copyright: 2000-08-01
• Publisher: Pharmaceutical Pr

Summary

Pathology and Therapeutics for Pharmacists was the first text to take an integrated approach to the pathophysiological and pharmacotherapeutic principles underlying the treatment of disease, and was based on many years experience of teaching one of the pioneering undergraduate clinical pharmacy courses in the UK. This edition has been completely revised and updated to reflect advances in therapeutic practice and the understanding of many disease states. Recent references and an updated reading list have been included along with the use of Recommended International Non-proprietary Names (rINN) for drug nomenclature. Read extensively worldwide, Pathology and Therapeutics for Pharmacists is an essential textbook for undergraduate pharmacists but will also be of interest outside the confines of pharmacy, reflecting the integrated nature of modern healthcare.

Table of Contents

Dedication and acknowledgements	xi
Preface to the second edition	xiii
Extract from preface to the first edition	xv
Recommended reference sources	xvii
Abbreviations	xix
Note on drug nomenclature	xxv
Plate section between pages 678 and 679
Therapeutics: general strategy	1	(18)
Terminology of disease	2	(4)
Case history	6	(5)
Drug selection	11	(6)
References and further reading	17	(2)
Major pathological processes in disease	19	(32)
Immunology	21	(14)
Inflammation	35	(11)
Ischaemia	46	(4)
References and further reading	50	(1)
Cardiovascular system	51	(98)
Physiological principles of the cardiovascular system	52	(16)
Clinical features of cardiovascular disease	68	(4)
Heart failure	72	(21)
Hypertension	93	(23)
Ischaemic heart disease	115	(1)
Atherosclerosis and vascular obstructive disease	116	(13)
Angina pectoris	129	(8)
Myocardial infarction	137	(9)
References and further reading	146	(3)
Renal system	149	(66)
Physiological principles of the renal system	150	(12)
Clinical features and investigation of renal disease	162	(14)
Renal failure	176	(15)
Renal replacement therapy	191	(12)
Important renal disease	203	(11)
References and further reading	214	(1)
Respiratory diseases	215	(82)
Anatomy and clinical physiology of the respiratory system	216	(9)
Clinical aspects of respiratory disease	225	(10)
Obstructive pulmonary disease	235	(1)
Asthma	235	(26)
Other allergic lung diseases	261	(1)
Chronic obstructive pulmonary disease (COPD)	262	(11)
Restrictive lung disease (RLD)	273	(1)
Diseases of the pulmonary circulation	273	(4)
Respiratory infections	277	(2)
Respiratory failure	279	(1)
Inhalation therapy	280	(11)
Oxygen therapy	291	(3)
References and further reading	294	(3)
Gastrointestinal and liver diseases	297	(86)
Gastrointestinal anatomy and physiology	298	(9)
Investigation	307	(3)
Disorders of the upper gastrointestinal tract	310	(1)
Oesophageal disorders	310	(6)
Helicobacter infection as a cause of gastroduodenal disease	316	(2)
Dyspepsia	318	(2)
Peptic ulcer disease	320	(12)
Nausea and vomiting	332	(3)
Problems of the small and large intestine	335	(1)
Malabsorption	335	(3)
Inflammatory bowel disease	338	(8)
Other colonic and rectal disorders	346	(8)
Stomatherapy	354	(5)
Liver diseases	359	(1)
Clinical physiology of the liver	359	(4)
Clinical features of hepatic disease	363	(8)
Gallstones (cholelithiasis)	371	(2)
Liver failure	373	(3)
Viral and other infective hepatitis	376	(3)
Drugs and the liver	379	(3)
References and further reading	382	(1)
Central nervous system	383	(80)
Physiological principles	384	(5)
Psychiatric disorder	389	(1)
Clinical aspects of psychiatric disorder	389	(2)
Anxiety	391	(11)
Depression	402	(17)
Mania and manic-depressive disorder	419	(3)
Schizophrenia	422	(17)
Neurological disorder	439	(1)
Parkinson's disease and the extrapyramidal syndromes	439	(10)
Epilepsy	449	(13)
References and further reading	462	(1)
Rheumatology: musculoskeletal and connective tissue diseases	463	(62)
Introduction	464	(1)
Anatomy and physiological principles of the musculoskeletal system	464	(4)
The immune system and rheumatic diseases	468	(2)
Examination, investigation and assessment	470	(4)
Osteoarthritis (OA, osteoarthrosis)	474	(5)
Rheumatoid arthritis (RA)	479	(24)
Seronegative spondarthritides	503	(1)
Ankylosing spondylitis (AS)	503	(2)
Reiter's syndrome	505	(1)
Crystal deposition arthropathies	505	(1)
Common features and pathology	505	(1)
Gout	506	(5)
Pyrophosphate arthropathy	511	(1)
Multisystem disorders and associated diseases	511	(1)
Systemic lupus erythematosus (SLE)	511	(3)
Sjogren's syndrome (keratoconjunctivitis sicca)	514	(1)
Scleroderma and systemic sclerosis	515	(1)
Raynaud's syndrome	516	(1)
Vasculitides	517	(2)
Other multisystem diseases	519	(1)
Other rheumatic diseases	520	(1)
Reactive arthritis	520	(1)
Soft tissue rheumatism	521	(3)
References and further reading	524	(1)
Diabetes mellitus	525	(46)
Epidemiology and classification	526	(1)
Physiological principles of glucose and insulin metabolism	527	(6)
Aetiology and pathogenesis	533	(2)
Clinical features	535	(1)
Complications	536	(10)
Management	546	(22)
Monitoring	568	(2)
References and further reading	570	(1)
Pain and its treatment	571	(48)
Introduction	572	(1)
Pathophysiology of pain	573	(2)
Principles of analgesic use	575	(5)
Analgesic drugs and techniques	580	(1)
Opioid analgesics	580	(10)
Less potent analgesics	590	(1)
Analgesic adjuvants	591	(2)
Other methods of pain control	593	(1)
Local anaesthetics	593	(3)
Topical agents	596	(1)
Physical methods	596	(1)
Techniques recruiting endogenous inhibitory mechanisms	596	(1)
Chemical nerve blocks	597	(2)
Neurosurgical approaches	599	(1)
Psychotherapy and hypnosis	599	(1)
Patient-controlled analgesia (PCA)	600	(1)
Common pain situations	601	(1)
Headache, migraine and facial pain	601	(12)
Post-herpetic neuralgia	613	(1)
Some special pain situations	614	(4)
References and further reading	618	(1)
Neoplastic disease	619	(52)
Classification and epidemiology of cancer	620	(3)
Aetiology	623	(3)
Pathobiology	626	(5)
Cytokinetics	631	(8)
Clinical features	639	(2)
Investigation and diagnosis	641	(1)
Management: aims and strategy	642	(3)
Chemotherapy of cancer	645	(24)
References and further reading	669	(2)
Skin diseases	671	(48)
Skin anatomy and physiology	672	(3)
Clinical features of skin diseases	675	(7)
Management of skin diseases	682	(10)
Psoriasis	692	(9)
Eczema and dermatitis	701	(6)
Acne	707	(6)
Rosacea	713	(1)
Urticaria	714	(2)
Drug-induced skin disease	716	(1)
The skin as a route for systemic drug delivery	716	(1)
References and further reading	717	(2)
Infections and antimicrobial therapy	719	(38)
Introduction	720	(1)
Classification of microorganisms	720	(1)
Classification and properties of antimicrobials	721	(2)
Penicillins	723	(2)
Cephalosporins	725	(2)
Aminoglycosides	727	(1)
Other antimicrobial agents	728	(5)
Therapeutic decisions in antimicrobial therapy	733	(9)
Some important infections	742	(13)
References and further reading	755	(2)
Index	757