Pathophysiology : The Biologic Basis for Disease in Adults and Children

by McCance, Kathryn L.; Huether, Sue E.; Brashers, Valentina L.; Rose, Neal S., Ph.d.

• ISBN13: 9780323065849
• ISBN10: 0323065848
• Additional ISBN(s): 9780323035071, 9780323088541
• Edition: 6th
• Format: Hardcover
• Copyright: 2009-11-19
• Publisher: Elsevier Science Health Science div
• More Book Details

Summary

Well-known for its authoritative and comprehensive coverage, complete treatment of pediatric pathophysiology, and the most extensive illustration program in its field, this textbook features expert content on everything from the general principles of pathophysiology to detailed discussions of genetics and specific diseases. Chapters on alteration present the pathophysiology, clinical manifestations, and evaluation and treatment of each disease to help you learn to identify normal anatomy and physiology, as well as alterations of function in adults and in children. Unparalleled coverage of disease processes makes this text the most comprehensive pathophysiology text available.The largest full-color art program in the field illustrates the clinical manifestations of diseases and disease processes Consistent presentations of each disease with pathophysiology, clinical manifestations, and evaluation and treatment help you find the information you need quickly and easily.Ten separate pediatric chapters cover the pathophysiologic effects on children. Aging content is highlighted throughout the text. An Introduction to Pathophysiology section at the beginning of the text provides a solid start to the basics of the study of disease. Algorithms and flowcharts of diseases and disorders illustrate the disease process in an easy-to-understand format.Nutrition and Disease boxes present evidence-based information on the relationship between health promotion through diet and disease.Updated content on leukocytes in pain modulation, seizure disorders, brain injuries and disorders, acute encephalopathies, reproductive disorders, and much more keep you at the cutting edge of this constantly changing field.What's New? boxes highlight the most current research and findings to ensure you have the most up-to-date information. New animations, review questions, Key Points, and an audio glossary have been added to the Evolve companion website to strengthen your understanding of key concepts. Media Resources Lists encourage you to develop a study plan to master the important content in each chapter.

Table of Contents

Introduction to Pathophysiology

Central Concepts Of Pathophysiology: Cells And Tissues

The Cell

Cellular Biology

Altered Cellular and Tissue Biology

The Cellular Environment: Fluids and Electrolytes, Acids and Bases

Genes and Gene-Environment Interaction

Genes and Genetic Diseases

Genes, Environment, Life-style, and Common Diseases

Mechanisms of Self-Defense

Innate Immunity: Inflammation

Adaptive Immunity

Alterations in Immunity and Inflammation

Infection

Stress and Disease

Cellular Proliferation: Cancer

Biology, Clinical Manifestations, and Treatment of Cancer

Cancer Epidemiology

Cancer in Children

Pathophysiologic Alterations: Organs And Systems

The Neurologic System

Structure and Function of the Neurologic System

Pain, Temperature Regulation, Sleep, and Sensory Function

Alterations in Cognitive Systems, Cerebral Hemodynamics and Motor Function

Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction

Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders

Alterations of Neurologic Function in Children

The Endocrine System

Mechanisms of Hormonal Regulation

Alterations of Hormonal Regulation

The Reproductive Systems

Structure and Function of the Reproductive Systems

Alterations of the Reproductive Systems

Sexually Transmitted Infections

The Hematologic System

Structure and Function of the Hematologic System

Alterations of Erythrocyte Function

Alterations of Leukocyte, Lymphoid, and Hemostatic Function

Alterations of Hematologic Function in Children

The Cardiovascular and Lymphatic Systems

Structure and Function of the Cardiovascular and Lymphatic Systems

Alterations of Cardiovascular Function

Alterations of Cardiovascular Function in Children

The Pulmonary System

Structure and Function of the Pulmonary System

Alterations of Pulmonary Function

Alterations of Pulmonary Function in Children

The Renal and Urologic System

Structure and Function of the Renal and Urologic Systems

Alterations of Renal and Urinary Tract Function

Alterations of Renal and Urinary Tract Function in Children

The Digestive System

Structure and Function of the Digestive System

Alterations of Digestive Function

Alterations of Digestive Function in Children

The Musculoskeletal System

Structure and Function of the Musculoskeletal System

Alterations of Musculoskeletal Function

Alterations of Musculoskeletal Function in Children

The Integumentary System

Structure, Function, and Disorders of the Integument

Alterations of the Integument in Children

Multiple Interacting Systems

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults

Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children

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