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9780521177481

Pathway Analysis and Optimization in Metabolic Engineering

by
  • ISBN13:

    9780521177481

  • ISBN10:

    0521177480

  • Format: Paperback
  • Copyright: 2011-04-28
  • Publisher: Cambridge University Press

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Summary

This book introduces researchers and advanced students in biology and engineering to methods of optimizing biochemical systems of biotechnological relevance. It examines the development of strategies for manipulating metabolic pathways, demonstrates the need for effective systems models, and discusses their design and analysis, while placing special emphasis on optimization. The authors propose power-law models and methods of Biochemical Systems Theory toward these ends. All concepts are derived from first principles, and the text is richly illustrated with numerous graphs and examples throughout.

Table of Contents

Preface
Target: a useful model
Methods of biochemical systems theory
A model of citric acid production in the mold Aspergillus niger
Optimization methods
Optimization of biochemical systems
Optimization of citric acid production in Aspergillus niger
Maximization of ethanol and carbohydrate production in Saccharomyces cerevisiae
Conclusions
Author index
Subject index
Table of Contents provided by Publisher. All Rights Reserved.

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