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9780340661901

Pediatrics and Perinatology The Scientific Basis

by ;
  • ISBN13:

    9780340661901

  • ISBN10:

    0340661909

  • Edition: 2nd
  • Format: Hardcover
  • Copyright: 1996-10-10
  • Publisher: Hodder Education Publishers
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List Price: $133.33

Summary

This second edition of the successful textbook Perinatal and Pediatric Pathophysiology addresses the physiological mechanisms by which the fetus, newborn, and child grow and develop normally. All major organ systems are covered including the immune and cardiovascular system. In addition, biological areas specific or particularly important to these developmental periods, for example growth and temperature regulation, are covered separately. The Second Edition has been extensively updated including two new chapters on genetics and bone, connective tissue, and skin development. Also, the chapters on membrane, cellular, and molecular biology, immunology, and on the nervous and muscle system have been totally rewritten. The chapter on neurophysiology is greatly extended with reference to both basic physiology and developmental aspects. Completely revised and up-to-date, the new edition of this essential textbook will prove invaluable reading for all those involved in pediatric research.

Table of Contents

Membrane and cellular biology
Molecular biology
Membrane and cellular structure and function
Genetics
Mechanisms
Genetic Mechanisms of human disease
Biochemistry and metabolism
Protein and amino acid metabolism
Amminia metabolism: urea cycle
Purine and pyrimidine metabolism
Fat and carbohydrate metabolism
Biochemical aspects of arachidonic acid metabolism
Free radicals, oxidants and antioxidants
Nitric oxide
Phases of development
Morphogenesis and teratogenesis
The physiology and pathophysiology of fetal sexual differentiation
The placenta
Fetal physiology
Parturition and regulation of uterine activity
Puberty
Growth
Tissue and organ growth
Regulation of cell replication
The role of growth factors in tissue development
Prenatal growth
Pathophysiology of intrauterine growth failure
Impact of perinatal nutrition on postnatal growth and metabolism
Postnatal growth
The nervous and muscle system
Overview
Basic neurophysiology
Development of the nervous system
Sensory systems
Motor systems
Biological rhythms, sleep and psychological developments
Vegetative functions
Cerebrovascular regulation
Nervous system pathophysiology
Skeletal muscle
The endocrine system
General principles of endocrinology
Neuroendocrine mechanisms
Growth hormone
Prolactin
The hypothalamic-pituitary-thyroid axis
Gonada and gonadotrophins
The adrenal cortex
Vasopressin and oxytocin
Hormonal regulation of the cardiovascular system, fluids and electrolytes
The adrenal medulla
Calcium, magnesium and phosphorous
Bone, connective tissue and skin
Bone and cartilage
Connective tissue
Skin
Wound healing
Thermoregulation
Thermoregulation
Fever andantipyresis
The gastrointestinal system and nutrition
Introduction
Structural development of the GI tract
Intestinal blood flow
Gastrointestinal hormones
Food ingestion and GI motility
Gastric acid secretion and gastroduodenal mucosal defense mechanisms
Intraluminal digestion and absorption in the small intestine
Absorption and secretion of electrolytes and fluid by the intestine
The nutritional role of the colon
GI immunology
Development and function of exocrine pancreas
Embryology and anatomy of the liver
Fetal and postnatal liver blood flow
Development of gallbladder motility
Bile acid metabolism and enterohepatic circulation of bile acids
Perinatal bilirubin metabolism
Nutritional requirements
Cardiovascular system
Vascular development and function
Cardiac and myocardial structure and myocardial cellular and molecular function
Myocardial receptors
Myocardial nervous innervation and regulation
Coronary circulation and myocardial oxygen consumption
Ventricular function
Specific circulations
Circulatory changes during gestation
Oxygen transport
Electrophysiology
Respiratory system: Pulmonary structure and function
Control of breathing
Mechanics of breathing
Blood
Leukopoiesis and the lymphoid system
Red cell physiology
The immune system
Ontogeny of the immune system
B-Cells
T-Cells
Hypersensitivity immune responses
Renal function, fluid and electrolyte balance
Anatomical development of the kidney
Renal hemodynamics
Glomerular filtration
Tubular function
Acid-base regulation
Regulation of water balance
Developmental pharmacology
Principles of pharmokinetics and pharmodynamics
Perinatal toxicology
Drug transfer into human milk
Index
Table of Contents provided by Publisher. All Rights Reserved.

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