Perinatal Stem Cells

by Cetrulo, Kyle; Cetrulo, Curtis L.; Taghizadeh, Rouzbeh R.

• ISBN13: 9781118209448
• ISBN10: 1118209443
• Edition: 2nd
• Format: Hardcover
• Copyright: 2013-03-18
• Publisher: Wiley-Blackwell

Summary

Perinatal Stem Cells, 2nd Edition builds on the first edition to provide an updated tutorial on perinatal stem cells, including stem cells harvested from the amniotic fluid, placenta, maternal blood supply, umbilical cord and Wharton's Jelly. As in the first edition, coverage includes the underlying biology of each of the sources of pregnancy related stem cells, cell culture, and potential therapeutic uses, as well as insights on the impact of these stem cells from obstetricians and gynecologists, cardiologists, hematologists, tissue engineers, and cord blood bankers. Normally discarded as medical waste, perinatal stem cells offer a powerful therapeutic tool box alternative to the controversial embryonic stem cells. Since publication of the first edition, a burgeoning commerical industry has developed around various sources of perinatal cells, and the second edition now includes an overview of this growing industry. With contributions from some of the top academic stem cell laboratories in the United States as well as new chapters from international stem cell scientists, Perinatal Stem Cells presents and update on the cutting-edge research in the field while maintaining its signature clinical focus.

Author Biography

Kyle J. Cetrulo is the founder and CEO of Auxocell Laboraties, Inc, as well as the founder and Director of the Perinatal Stem Cell Society.?Co-editor of the first edition of Perinatal Stem Cells, Dr. Cetrulo is an active member of the stem cell research community, serving as Director of the International Cord Blood Society since 1998.

Curtis Cetrulo Jr., M.D. is Assistant Professor of Surgery at Harvard Medical School, Boston. A co-editor of the first edition of Perinatal Stem Cells, he is also Director of the Reconstructive Transplantation Service in the Divisions of Transplant Surgery and Plastic and Reconstructive Surgery at Massachusetts General Hospital, and a senior investigator for the Composite Tissue Allograft Laboratory at Massachusetts General.

Table of Contents

List of Contributors

Introduction

1. Amniotic Fluid Stem Cells
Sean Vincent Murphy and Anthony Atala

2. Cord Blood Transplants:  Perinatal Stem Cells in Clinical Practice
Richard L. Haspel and Karen K. Ballen

3. Hematopoietic Stem Cell Development in the Placenta
Katrin E. Rhodes, Akanksha Chhabra and Hanna K.A. Mikkola

4. Perinatal Mesenchymal Stem Cell Banking for Umbilical Cord Blood Transplantation and Regenerative Medicine
Rouzbeh R. Taghizadeh

5. Making Organ and Stem Cell Transplantation Safer: The Role of Mesenchymal Stem Cells
Hans Klingemann

6. Wharton?s Jelly Mesenchymal Stem Cells and Immune Modulation: Regenerative Medicine Meets Tissue Repair
Rita Anzalone, Felicia Farina, Melania Lo Iacono, Simona Corrao, Tiziana Corsello, Giovanni Zummo, and Giampiero La Rocca

7. Immungenicity Vs. Immunomodulation of Perinatal Stem Cells
Bram Lutton and Raimon Duran-Struuck

8. The Translational Potential of Perinatal Stem Cells in Clinical Medicine: Mesenchymal Stem Cells
Radbeh Torabi,  Vincenzo Villani, Christopher A. Mallard, and Curtis L. Cetrulo, Jr.

9. Newborn Stem Cells ? Identity, Function and Clinical Potential
Anthony Park, Ann Chidgey, Sean Murphy, Ursula Manuelpillai and Richard Boyd

10. Biomedical Potential of Human Perinatal Stem Cells
Oleg V. Semenov and Christian Breymann

11. Progenitor Cell Therapy for the Treatment of the Traumatic Brain Injury
Alex Bryan Olsen, Robert A. Hetz, Supinder S. Bedi, and Charles S. Cox, Jr.

12. The Human Amniotic Membrane: A Tissue with Multifaceted Properties and Different Potential Clinical Applications
Maddalena Caruso, Antonietta Silini, and Ornella Parolini

13. Advances and Possibile Applications of Human Amnion for the Management of Liver Disease
Fabio Marongiu, Marc C. Hansel, Kristen J. Skvorak, Maria Paola Serra, Marcella Sini, Roberto Gramignoli, Ezio Laconi and Stephen C. Strom

14. Amnion-Derived Cells for Stroke Restorative Therapy
Loren E. Glover, Naoki Tajiri and Cesar V. Borlongan

15. Pregnancy-Acquired Fetal Progenitors as Natural Cell Therapy
Elke Seppanen, Nicholas Fisk, and Kiarash Khosrotehrani

Industry Review

16. Perinatal Stem Cells ? An Industry Perspective
 Kyle J. Cetrulo

17. Patent Protection of Stem Cell Innovations:  The Role of Patents in Commercialization
John R. Wetherell

18. Interview with Frances Verter ? Founder of Parent?s Guide to Cord Blood Foundation
Frances Verter and Kyle J. Cetrulo

19. Umbilical Cord Blood Banking: An Obstetricians Perspective
Jordan H. Perlow