Persistent, Bioaccumulative, and Toxic Chemicals Volume II: Assessment and New Chemicals

by Lipnick, Robert L.; Jansson, Bo; Mackay, Donald; Petreas, Myrto

• ISBN13: 9780841236752
• ISBN10: 0841236755
• Format: Hardcover
• Copyright: 2000-12-07
• Publisher: American Chemical Society

Summary

This is part of a two-book assessment of hydrolase structure/functionrelationships and the means by which these important enzymes can be betterutilized. Each book, Assessment and Emerging New Chemicals and Fate andExposure, will deal with understanding cellulase and hemicellulase action - astrategy based in macromolecular modeling, site-directed mutagenesis, activesite mapping, heterologous expression, and classical kinetic characterization.Information about new cellulase enzymes and systems and trends in the field ofglycosyl hydrolase biochemistry will be examined as well as new crystallographicstructure of important cellulases and methods for improving activity by proteinengineers.

Table of Contents

Preface	xi
Identification of Persistent, Bioaccumulative, and Toxic Substances	1	(13)
Bo Jansson
Robert L. Lipnick
Donald Mackay
Myrto Petreas
Persistence and Modeling
Defining the Bioaccumulation, Persistence, and Transport Attributes of Priority Chemicals	14	(15)
Donald Mackay
Eva Webster
Andreas Beyer
Michael Matthies
Frank Wania
CART Screening Level Analysis of Persistence: A Case Study	29	(13)
Deborah H. Bennett
Thomas E. McKone
W. E. Kastenberg
Environmental Categorization and Screening of the Canadian Domestic Substances List	42	(10)
Roger Breton
Robert Chenier
Relationship between Persistence and Spatial Range of Environmental Chemicals	52	(12)
Martin Scheringer
Deborah H. Bennett
Thomas E. McKone
Konrad Hungerbuhler
Application of Negligible Depletion Solid-Phase Extraction (nd-SPE) for Estimating Bioavialability and Bioaccumulation of Individual Chemicals and Mixtures	64	(11)
Joop L. M. Hermens
Andreas P. Freidig
Enaut Urrestarazu Ramos
Wouter H. J. Vaes
Willem M. G. M. van Loon
Eric M. J. Verbruggen
Henk J. M. Verhaar
Modeling Historical Emissions and Environmental Fate of PCBs in the United Kingdom	75	(14)
Andrew J. Sweetman
Kevin C. Jones
Estimating Accumulation and Baseline Toxicity of Complex Mixtures of Organic Chemicals to Aquatic Organisms: The Use of Hydrophobicity Dependent Analytical Methods	89	(11)
Eric M. J. Verbruggen
Joop L. M. Hermens
Selection and Evaluation of Persistent, Bioaccumulative, and Toxic Criteria for Hazard Assessment	100	(14)
Han Blok
Froukje Balk
Peter Okkerman
Dick Sijm
An Environmental Protection Agency Multimedia Strategy for Priority Persistent, Bioaccumulative, and Toxic Pollutants	114	(10)
Sam Sasnett
Thomas Murray
Sheila Canavan
John Alter
Kathy Davey
Paul Matthai
Dioxin Pollution Prevention Inventory for the San Francisco Bay	124	(14)
Greg Karras
U.S. Environmental Protection Agency New Chemicals Program PBT Chemical Category: Screening and Risk Management of New PBT Chemical Substances	138	(13)
Kenneth T. Moss
Robert S. Boethling
J. Vincent Nabholz
Charles M. Auer
The U.S. Environmental Protection Agency Minimization Prioritization Tool: Computerized System for Prioritizing Chemicals Based on PBT Characteristics	151	(33)
Mark D. Ralston
Daniel L. Fort
Jay H. Jon
James K. Kwiat
New Chemicals
Short Chain Chlorinated Paraffins: Are They Persistent and Bioaccumulative?	184	(19)
Derek Muir
Don Bennie
Camilla Teixeira
Aaron Fisk
Gregg Tomy
Gary Stern
Mike Whittle
Polycyclic Musk Fragrances in the Aquatic Environment	203	(20)
Hermann Fromme
Thomas Otto
Konstanze Pilz
Polychlorinated Naphthalenes in the Atmosphere	223	(12)
Tom Harner
Terry F. Bidleman
Robert G. M. Lee
Kevin C. Jones
Polybrominated Diphenyl Ethers (PBDEs) in Human Milk from Sweden	235	(8)
S. Atuma
M. Aune
P. O. Darnerud
S. Cnattingius
M. L. Wernroth
A. Wicklund-Glynn
Characterization of Q1, an Unknown Major Organochlorine Contaminant in the Blubber of Marine Mammals from Africa, the Antarctic, and Other Regions	243	(17)
W. Vetter
Author Index	260	(1)
Subject Index	261