Pharmacoeconomics in Perspective

by Bonk; Robert J

• ISBN13: 9780789005618
• ISBN10: 0789005611
• Format: Hardcover
• Copyright: 1999-06-02
• Publisher: CRC Press

Summary

Through Pharmacoeconomics in Perspective: A Primer on Research, Techniques, and Information, you will discover the means to self-defend against unscrupulous promotion of new drugs, unfounded conclusions in literature, and inappropriate methods for research studies. You will find the material in this book straightforward, logical, and most importantly, understandable.

Author Biography

Robert J. Bonk, PhD, is a supplemental faculty member at the University of Delaware, Drexel University, and the University of the Sciences in Philadelphia

Table of Contents

Foreword	xi
Albert I. Wertheimer
Preface	xiii
Acknowledgments	xv
PART I: BASICS OF PHARMACOECONOMIC RESEARCH	1	(22)
Pharmacoeconomics As Outcomes Research	3	(4)
Unique Position of Health Care	4	(1)
Outcomes of Health Care Programs	4	(1)
Development of a Critical Perspective	5	(2)
Health Care Expenditures and Pharmacoeconomics	7	(4)
Focus on Health Care Expenditures	7	(1)
Emphasis on Prescription Drugs	8	(1)
Tools for Expenditure Decisions	9	(2)
Pharmacoeconomics Within Drug Development	11	(12)
Overview of Drug Development	11	(4)
Regulations for Pharmacoeconomic Data	15	(1)
Integration of Pharmacoeconomic Research	16	(3)
Pharmacoeconomic Research	19	(1)
Questions	19	(1)
Answers	20	(3)
PART II: TYPES OF PHARMACOECONOMIC ANALYSES	23	(34)
Cost-of-Illness Analysis	25	(4)
Baseline Measures of Cost	25	(1)
Cost-of-Illness Examples	26	(3)
Cost-Benefit Analysis	29	(6)
Common Denominator for Comparison	29	(2)
Applications of Cost-Benefit Analysis	31	(1)
Cost-Benefit Examples	32	(3)
Cost-Effectiveness Analysis	35	(6)
Therapeutic Measures of Effectiveness	35	(2)
Applications of Cost-Effectiveness Analysis	37	(1)
Cost-Effectiveness Examples	38	(3)
Cost-Utility Analysis	41	(6)
Measurements of Utility	41	(2)
Cost-Utility Examples	43	(4)
Cost-Minimization Analysis	47	(10)
Equivalency of Outcomes	47	(1)
Cost-Minimization Examples	48	(5)
Pharmacoeconomic Analyses	53	(1)
Questions	53	(2)
Answers	55	(2)
PART III: TECHNIQUES OF PHARMACOECONOMIC RESEARCH	57	(28)
Perspectives for Research Analyses	59	(6)
Perspectives for Pharmacoeconomics	60	(1)
Scenarios of Perspective	61	(1)
Repercussions of Perspective	62	(3)
Determination of Outcome Measures	65	(6)
Alternatives for Clinical Decisions	65	(3)
Delineation of Outcome Measures	68	(3)
Categorization of Pharmacoeconomic Costs	71	(6)
Key Categories of Costs	71	(2)
Issues in Calculating Costs	73	(4)
Sensitivity Analysis of Assumptions	77	(8)
Rationale for Sensitivity Analysis	77	(2)
Methods for Testing Sensitivity	79	(2)
Pharmacoeconomic Techniques	81	(1)
Questions	81	(1)
Answers	82	(3)
PART IV: EVALUATION OF PHARMACOECONOMIC INFORMATION	85	(18)
Review of Pharmacoeconomic Research	87	(4)
Steps in Pharmacoeconomic Research	87	(2)
Factors in Research Evaluation	89	(2)
Regulatory and Ethical Considerations	91	(4)
Influence of Regulatory Guidelines	91	(1)
Issues of Ethical Concern	92	(3)
Sources for Pharmacoeconomic Information	95	(8)
Books	95	(1)
Journals	96	(1)
Databases	97	(2)
Pharmacoeconomic Information	99	(1)
Questions	99	(1)
Answers	100	(3)
References	103	(8)
Index	111