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9781420054583

Pharmacokinetics and Pharmacodynamics of Abused Drugs

by ;
  • ISBN13:

    9781420054583

  • ISBN10:

    1420054589

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2007-10-09
  • Publisher: CRC Press

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Summary

Pharmacokinetics and Pharmacodynamics of Abused Drugs is a concise and focused volume devoted to the metabolism and measurable effects of drugs on the human body. Beginning with basic concepts and models designed to provide a fundamental understanding of the subject matter, the book details the specifics of absorption, distribution, and elimination pathways and rates of commonly abused drugs. It analyzes the effects of drug use on human performance including response time, memory and recall, logical and cognitive processes, as well as physiological changes. Packed with data and comparative studies, this handy volume considers the effects of marketed and prescription medications as well as illicit drugs including opioids, cannabis, cocaine, methamphetamine, MDMA, ketamine, nicotine, and LSD. Containing 29 figures and tables and extensive references, this is a must-have resource for the influence of drug use and abuse on human physiology and performance.

Table of Contents

Pharmacokinetics: Basic Concepts and Modelsp. 1
Pharmacokinetic Modeling and Pharmacokinetic-Pharmacodynamic Correlationsp. 15
Toxicokinetics and Factors Affecting Pharmacokinetic Parametersp. 21
Pharmacokinetics of Specific Drugsp. 25
Pharmacodynamics: Effects of Abused Drugs on Human Performance: Laboratory Assessmentp. 65
Performance-Based Assessment of Behavioral Impairment in Occupational Settingsp. 97
Pupillometry and Eye Tracking as Predictive Measures of Drug Abusep. 127
Abuse of Marketed Medicationsp. 143
Indexp. 175
Table of Contents provided by Ingram. All Rights Reserved.

Supplemental Materials

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