Pharmacology : With Student Consult Online Access

by Rang, H. P.; Dale, M. M.; Ritter, J. M.; Flower, R. J.

• ISBN13: 9780443069116
• ISBN10: 0443069115
• Edition: 6th
• Format: Paperback
• Copyright: 2007-01-25
• Publisher: Elsevier Science Health Science div

Summary

A straightforward way to master a complex subject! This bestselling textbook presents all the knowledge you need to get through your pharmacology course and beyondusing a clear and accessible approach that makes the material easy and interesting to learn. Progressing logically from a molecular understanding of receptors and drug actions to the clinical uses of the most important groups of drugs, it delivers the latest information on cannabinoids and rimonabant, Cox 2 inhibitors, pharmacogenetics, biopharmaceuticals, and drug abuseas well as "lifestyle drugs" such as performance-enhancing substances, botulinum toxin, and Viagra®. And now, online access via STUDENT CONSULT makes it an even more effective learning resource! Progresses logically from a molecular understanding of receptors and drug actions to the clinical uses of the most important groups of drugs. Covers recent developments in areas such as cannabinoids and rimonabant, Cox 2 inhibitors, pharmacogenetics, biopharmaceuticals, and drug abuse. Discusses "lifestyle drugs" such as performance-enhancing substances, botulinum toxin, and Viagra®. Uses superb full-color illustrations to clarify even the most complex concepts, and color-coded chapters to make navigation easy. Includes STUDENT CONSULT access at no additional charge, enabling you to consult the book online, anywhere you go perform quick searches add your own notes and bookmarks follow Integration Links to related bonus content from other STUDENT CONSULT titlesto help you see the connections between diverse disciplines test your knowledge with multiple-choice review questions and more!

Table of Contents

Preface	p. vii
Acknowledgements	p. viii
Abbreviations and acronyms	p. ix
General principles
What is pharmacology?	p. 3
How drugs act: general principles	p. 8
How drugs act: molecular aspects	p. 24
How drugs act: cellular aspects-excitation, contraction and secretion	p. 54
Cell proliferation and apoptosis	p. 72
Method and measurement in pharmacology	p. 87
Absorption and distribution of drugs	p. 98
Drug elimination and pharmacokinetics	p. 113
Chemical mediators
Chemical mediators and the autonomic nervous system	p. 131
Cholinergic transmission	p. 144
Noradrenergic transmission	p. 168
Other peripheral mediators: 5-hydroxytryptamine and purines	p. 189
Local hormones, inflammation and immune reactions	p. 202
Anti-inflammatory and immunosuppressant drugs	p. 226
Cannabinoids	p. 248
Peptides and proteins as mediators	p. 256
Nitric oxide	p. 265
Drugs affecting major organ systems
The heart	p. 277
The vascular system	p. 298
Atherosclerosis and lipoprotein metabolism	p. 321
Haemostasis and thrombosis	p. 331
The haemopoietic system	p. 347
The respiratory system	p. 356
The kidney	p. 368
The gastrointestinal tract	p. 385
The endocrine pancreas and the control of blood glucose	p. 397
Obesity	p. 410
The pituitary and the adrenal cortex	p. 420
The thyroid	p. 437
The reproductive system	p. 445
Bone metabolism	p. 461
The nervous system
Chemical transmission and drug action in the central nervous system	p. 473
Amino acid transmitters	p. 479
Other transmitters and modulators	p. 492
Neurodegenerative diseases	p. 508
General anaesthetic agents	p. 523
Anxiolytic and hypnotic drugs	p. 535
Antipsychotic drugs	p. 545
Antidepressant drugs	p. 557
Antiepileptic drugs	p. 575
Analgesic drugs	p. 588
CNS stimulants and psychotomimetic drugs	p. 610
Drug addiction, dependence and abuse	p. 619
Local anaesthetics and other drugs affecting sodium channels	p. 638
Drugs used in the treatment of infections and cancer
Drugs used in the treatment of infections and cancer	p. 647
Antibacterial drugs	p. 661
Antiviral drugs	p. 679
Antifungal drugs	p. 692
Antiprotozoal drugs	p. 698
Antihelminthic drugs	p. 712
Cancer chemotherapy	p. 718
Special topics
Individual variation and drug interaction	p. 739
Harmful effects of drugs	p. 751
Lifestyle drugs and drugs in sport	p. 765
Biopharmaceuticals and gene therapy	p. 770
Drug discovery and development	p. 781
Appendix	p. 787
Index	p. 797
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