Pharmacology and Therapeutics of Asthma and COPD

by Page, Clive P.; Barnes, Peter J.; Busse, W. (CON); Dziadzio, L. (CON); Erin, E. M. (CON); Fernandes, L. B. (CON)

• ISBN13: 9783540004646
• ISBN10: 3540004645
• Format: Hardcover
• Copyright: 2004-03-01
• Publisher: Springer Verlag

Summary

The aim of the book is to provide an in-depth review of our current understanding of the pathogenesis of both asthma and COPD. This volume also discusses the promising new options for pharmacological intervention of these diseases. Each chapter is extensively referenced, generously illustrated with clear diagrams and photographs, and represents a state-of-the-art review of this important area of lung biology.

Table of Contents

Part 1. Current Drugs
β-Adrenoceptor Agonists	3	(34)
L.B. Fernandes, P.J. Henry, R.G. Goldie
Anticholinergic Bronchodilators	37	(16)
N.J. Gross
Theophylline in the Treatment of Respiratory Disease	53	(26)
N.A. Jones, C.P. Page
Corticosteroids	79	(46)
P.J. Barnes
Mediator Antagonists and Anti-Allergic Drugs	125	(28)
N.C. Thomson
Part 2. Future Drugs
New Bronchodilator Drugs	153	(26)
D. Spina
Selective Phosphodiesterase Inhibitors in the Treatment of Respiratory Disease	179	(40)
N.A. Jones, D. Spina, C.P. Page
Cytokine Modulators	219	(26)
P.J. Barnes
Inhibitors of Leucocyte-Endothelial Adhesion as Potential Treatments for Respiratory Disease	245	(28)
R. Lever, C.P. Page
New Antiallergic Drugs	273	(14)
L. Dziadzio, W. Neaville, W Busse
Pharmacogenetics, Pharmacogenomics and Gene Therapy	287	(16)
I.P. Hall
Evaluation of New Drugs for Asthma and COPD: Endpoints, Biomarkers and Clinical Trial Designs	303	(46)
P.J. Barnes, E.M. Erin, T.T. Hansel, S. Kharitonov, A.J. Tan, R.C. Tennant
Novel Anti-inflammatory Therapies	349	(24)
P.J. Barnes, C.P. Page
Subject Index	373