Pituitary Adenylate Cyclase-Activating Polypeptide

by Vaudry, Hubert; Arimura, Akira

• ISBN13: 9781402073069
• ISBN10: 1402073062
• Format: Hardcover
• Copyright: 2003-01-01
• Publisher: Kluwer Academic Pub

Summary

Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.

Table of Contents

List of contributors	vii
Preface	xv
H. Vaudry
A. Arimura
PACAP: Discovery, Gene, Receptors	1	(24)
A. Arimura
Molecular Evolution of PACAP Precursor and PACAP Receptors	25	(24)
B.K.C. Chow
R.T.K. Pang
S.S.M. Ng
Development of Selective Ligands for PAC1, VPAC1 and VPAC2 Receptors	49	(20)
P. Robberecht
P. Vertongen
I. Langer
J. Perret
Molecular Pharmacology and Structure-Function Analysis of PACAP/VIP Receptors	69	(26)
M. Laburthe
A. Couvineau
P. Nicole
PACAP Receptor Signaling	95	(30)
S. Shioda
C.J.I. Zhou
H. Ohtaki
T. Yada
Function of PACAP in the Central Nervous System	125	(28)
B.J. Gonzalez
D. Vaudry
M. Basille
C. Rousselle
A. Falluel-Morel
H. Vaudry
Function of PACAP in the Hypothalamo-Pituitary Complex	153	(32)
M.Malagon
J.P. Castano
S. Garcia-Navarro
A.J. Martinez-Fuentes
F. Gracia-Navarro
PACAP in the Endocrine Pancreas	185	(22)
B. Ahren
Function of PACAP in the Adrenal Cortex	207	(20)
G.G. Nussdorfer
PACAP: An `Emergency Response' Co-Transmitter in the Adrenal Medulla	227	(24)
C. Hamelink
E. Weihe
L.E. Eiden
PACAP in the Urogenital Tract	251	(26)
J. Fahrenkrug
J. Hannibal
S. Gras
Function of PACAP in the Cardiovascular System	277	(12)
A. Miyata
Function of PACAP in the Respiratory System	289	(16)
J.C. Prieto
Function of PACAP in the Immune System	305	(18)
M. Delgado
J. Leceta
R.P. Gomariz
PACAP Receptor Knockout and Transgenics. What Have We Learnt?	323	(24)
P. Brabet
F. Jamen
N. Rodriguez-Henche
G. Bertrand
J. Bockaert
Consequences of PACAP Gene Knockout	347	(14)
N.M. Sherwood
S.L. Gray
K.J. Cummings
The Biological Significance of PACAP and PACAP Receptors in Human Tumors: From Cell Lines to Cancers	361	(40)
V. Lelievre
N. Pineau
J.A. Waschek
Index	401