Polymeric Delivery of Therapeutics

by Morgan, Sarah; Lochhead, Robert

• ISBN13: 9780841225831
• ISBN10: 0841225834
• Format: Hardcover
• Copyright: 2011-04-15
• Publisher: American Chemical Society

Summary

Polymeric delivery of therapeutics applies to a wide range of applications, including medical, pharmaceutical, cosmetics, personal care and nutrition markets. Recent advances in polymer synthesis and characterization techniques, most notably new controlled living polymerization routes for synthesis of targeted molecular architectures and advanced techniques for manipulation and characterization of nanostructures in polymer matrices, enable advances in therapeutic delivery that were unimaginable a few years ago. Health, medical and personal care markets represent the fastest growing markets in the chemical industry in the US and world wide. This symposium series book includes contributions from academic and industrial researchers developing controlled polymer structures for delivery of therapeutics in biomedical, pharmaceutical, personal care and cosmetic applications, and includes a summary of intellectual property considerations in the field. It is intended to provide relevant and timely information for those involved in research and development in this rapidly growing field. The book is organized in four sections. The first section includes two comprehensive overview chapters, one devoted to advances in polymeric delivery for the cosmetic and personal care market and the other devoted to polymers in nano pharmaceuticals. The next section includes contributions on synthesis and analysis of polymers with controlled architectures for biomedical applications. The third section is devoted to industrial contributions with state-of-the-art developments in personal care applications. The final section provides information on recent trends in U.S. patent law for polymeric delivery of therapeutics.

Table of Contents

Preface	p. ix
Overview: Polymeric Delivery in Cosmetics and Personal Care
A Review of Recent Advances in the Polymeric Delivery of Attributes in Cosmetics and Personal Care Products	p. 3
Overview: Polymers in Nano Pharmaceuticals
Polymers in Nano Pharmaceutical Materials	p. 25
Polymers in Biomedical Applications: Controlled Polymer Structures
Rational Design of Biopolymers via Aqueous Reversible Addition-Fragmentation Chain Transfer Polymerization	p. 49
Surface Modification of Positive Contrast Nanoparticle Agents with RAFT Polymers Towards the Targeted Imaging and Treatment of Cancer	p. 65
Iron Chelating Macromolecules for Intravascular Iron Chelation Therapy	p. 103
Primary Amine-Functionalized Silicon Surfaces via Click Chemistry with a-Alkynyl-Functionalized Poly(2-aminoethyl methacrylate)	p. 113
Synthetic Reactive Polyelectrolytes for Cell Encapsulation	p. 131
Polymer/Dendrimer Supported Organoplatinum Drugs	p. 161
Storage and Release of Nitric Oxide from Molecular Sieve Nanoparticles	p. 181
Polymeric Delivery in Cosmetics and Personal Care Applications
Oil Absorption and Delivery System Polymer Technology for Skin and Hair Care	p. 195
Silicone Elastomeric Particles in Skin Care Applications	p. 207
A New Approach to Formulating Mild Cleansers: Hydrophobically-Modified Polymers for Irritation Mitigation	p. 221
Silicone Polyethers as Stabilizers of Water-in-Oil Emulsions	p. 243
Intellectual Property Considerations for Polymer Delivery of Theraputics
Recent Trends in the United States Patent Law	p. 269
Indexes
Author Index	p. 279
Subject Index	p. 281
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