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9780841239609

Polysaccharides for Drug Delivery and Pharmaceutical Applications

by ; ;
  • ISBN13:

    9780841239609

  • ISBN10:

    0841239606

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2006-06-22
  • Publisher: American Chemical Society

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Summary

Over the last decades we have seen the pharmaceutical industry grow at a tremendous rate. Along with the discoveries of drugs with novel and peculiar properties, the need for novel materials and methods to deliver them energized the field of drug delivery creating new opportunities for material scientists. Among those materials, the pharmaceutical industry has since the beginning relied on cellulose, the most abundant natural polymer on earth. Nowadays, many polysaccharides are used, modified and transformed to serve the pharmaceutical needs either as solubilizers, adhesives, carriers or active substances themselves. This book covers many of the polysaccharides used in the field, their sources, properties, preparation and mechanism of action.

Table of Contents

Overview of polysaccharides : nature's own polymers at the service of drug delivery
Fishing for proteins with magnetic cellulosic nanocrystalsp. 3
Applications of cellulose and cellulose derivatives in immediate release solid dosagep. 19
Hydroxypropylcellulose in oral drug deliveryp. 57
Contramid : high-amylose starch for controlled drug deliveryp. 79
Water diffusion in drug delivery systems made of high-amylose starch as studied by NMR imagingp. 105
Cross-linked starch derivatives for highly loaded pharmaceutical formulationsp. 121
Hyaluronan : investigations into the mode of action of hyaluronan in topical drug deliveryp. 141
Biomedical applications of hyaluronic acidp. 155
Chitosan nanoparticles for non-viral gene therapyp. 177
Chitosan as a biomaterial for preparation of depot-based delivery systemsp. 201
Characterization of glycol chitosan : a potential material for use in biomedical and pharmaceutical applications : a comparison of fractionation techniquesp. 227
Chitosan : a natural polycation with multiple applicationsp. 243
Properties of levan and potential medical usesp. 263
Iron-polysaccharide composites for pharmaceutical applicationsp. 271
Polysaccharide - drug conjugates as controlled drug delivery systemsp. 287
Polysaccharide hydrogels for the preparation of immunoisolated cell delivery systemsp. 305
Table of Contents provided by Blackwell. All Rights Reserved.

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