Practical Genetics for Primary Care

by Rose, Peter W.; Lucassen, Anneke

• ISBN13: 9780192629319
• ISBN10: 019262931X
• Format: Paperback
• Copyright: 1999-12-30
• Publisher: Oxford University Press

Summary

There are many books about genetics, but none have addressed the specific primary care aspects of genetics. This book addresses these and covers all the issues relevant to primary care. There is a user-friendly description of molecular biology terms and techniques which many GPs have no experience of, but which is increasingly relevant in the consulting room. Other aspects particularly relevant to primary care are covered, such as the skills needed by primary care workers to undertake genetic consultations together with discussions of models of care that will be helpful. The book covers in detail topics such as genetic mechanisms, ethics and the genetic tests available.

Table of Contents

List of contributors	ix
Introduction	1	(10)
Anneke Lucassen
Peter Rose
SECTION I: BASIC GENETICS
The cellular and molecular basis of inheritance	11	(14)
Anneke Lucassen
Patterns of inheritance	25	(18)
Anneke Lucassen
Laboratory techniques used in genetic testing	43	(14)
Anneke Lucassen
SECTION II: CLINICAL GENETICS
Taking a family history	57	(20)
Peter Rose
Counselling techniques	77	(26)
Peter Rose
Chromosomal abnormalities or cytogenetics	103	(12)
Anneke Lucassen
Clinical examples of single gene disorders	115	(30)
Anneke Lucassen
Genetics of multifactorial diseases	145	(22)
Anneke Lucassen
Familial cancers	167	(46)
Anneke Lucassen
Prenatal diagnosis	213	(34)
Patricia Boyd
The dysmorphic or syndromal child	247	(12)
Angus Dobbie
SECTION III: PRIMARY CARE PERSPECTIVES OF GENETICS
The organization of care	259	(14)
Peter Rose
Screening methods	273	(26)
Peter Rose
The primary--secondary care interface	299	(12)
Peter Rose
Ethical issues in clinical genetics	311	(20)
Anneke Lucassen
The patient's perspective	331	(8)
Aamra Darr
Appendix 1 Glossary of genetic terms	339	(8)
Appendix 2 Genetic sites on the Internet	347	(2)
Appendix 3 Regional Genetics Centres, UK	349	(6)
Appendix 4 United Kingdom cancer registries	355	(4)
Index	359