Practical Hemostasis and Thrombosis

by Key, Nigel; Makris, Michael; O'Shaughnessy, Denise; Lillicrap, David

• ISBN13: 9781444306286
• ISBN10: 1444306286
• Edition: 2nd
• Format: eBook
• Copyright: 2010-05-05
• Publisher: Wiley-Blackwell

Summary

This practical guide provides all the information necessary to understand the clotting mechanisms, as well as how to prevent, diagnose, and treat bleeding and clotting disorders. Practical Hemostasis and Thrombosis has been updated to reflect all the important advances made since the first edition. It includes an in-depth description of platelet abnormalities and disseminated intravascular coagulation, as well as covering the laboratory and molecular biological tests needed for the diagnosis of bleeding and clotting disorders.

Clinicians will find useful advice for everyday questions in each specialty area as the book describes hemorrhagic and thrombotic problems in cardiology, neurology, hepatology, nephrology, oncology, obstetrics, pediatrics, intensive care and transfusion medicine.

An invaluable resource for all hematologists, trainee hematologists preparing for examinations and clinicians this book should be kept close at hand for frequent consultation

Author Biography

Nigel Key, Department of Hematology, Oncology and Transplantation, University of North Carolina School of Medicine, North Carolina, Chapel Hill, USA

Michael Makris, Senior Lecturer in Haematology, Department of Medicine and Pharmacology, University of Sheffield, Sheffield, UK

Denise O'Shaugnessy, formerly Director, Haematology Laboratory, School of Medicine, Health and Biological Sciences; Southampton University Hospitals NHS Trust, Southampton General Hospital, Southampton and Blood Policy Group, Department of Health, UK

David Lillicrap, Professor of Hematology, Department of Pathology and Molecular Medicine, Richardson Laboratory, Queen's University, Kingston, Ontario, Canada.

Table of Contents

Contributors.

Foreword (Harold R. Roberts).

1 Basic principles underlying coagulation (Dougald M. Monroe).

2 Laboratory tests of hemostasis (Steven Kitchen and Michael Makris).

3 Laboratory evaluation and thrombophilia (Rajiv K. Pruthi and John A. Heit).

4 Molecular diagnostic approaches to hemostasis (Paula James and David Lillicrap).

5 Tests of platelet function (Paul Harrison).

6 Evaluation of the bleeding patient (Alice Ma).

7 Hemophilia A and B (Rhona M. Maclean and Michael Makris).

8 Von Willebrand disease (Giancarlo Castaman, Alberto Tosetto, and Francesco Rodeghiero).

9 The rarer inherited coagulation disorders (Paula Bolton-Maggs and Jonathan Wilde).

10 Quantitative platelet disorders (Jeremy D. Robertson, Victor S. Blanchette, and Walter H.A. Kahr).

11 Qualitative platelet disorders (Marco Cattaneo).

12 Disseminated intravascular coagulation and other microangiopathies (Raj S. Kasthuri and Nigel S. Key).

13 Venous thromboembolism (Lori-Ann Linkins and Clive Kearon).

14 Myeloproliferative neoplasms: Essential thrombocythemia, polycythemia vera, and primary myelofibrosis (Ayalew Tefferi).

15 Arterial thrombosis (Gordon D.O. Lowe and R. Campbell Tait).

16 Anticoagulation (Gualtiero Palareti and Benilde Cosmi).

17 Antiphospholipid syndrome (Henry G. Watson and Beverley J. Robertson).

18 Cardiology (Jeffrey S. Berger and Richard C. Becker).

19 Cardiothoracic surgery (Denise O’Shaughnessy and Ravi Gill).

20 Neurology (Natalie Aucutt-Walter, Valerie Jewells, and David Y. Huang).

21 Hepatology (Raj K. Patel and Roopen Arya).

22 Nephrology (Stephanie Perry and Thomas L. Ortel).

23 Oncology (Anna Falanga and Marina Marchetti).

24 Obstetrics, contraception, and estrogen replacement (Isobel D. Walker).

25 Pediatrics (Mary E. Bauman and M. Patricia Massicotte).

26 Intensive and critical care (Beverley J. Hunt).

27 Transfusion (Adrian Copplestone).

Appendix 1 Reference ranges (Steven Kitchen and Michael Makris).

Index.

Colour plate section.