Pre-eclampsia: Etiology and Clinical Practice

by Edited by Fiona Lyall , Michael Belfort

• ISBN13: 9780521831895
• ISBN10: 052183189X
• Edition: 1st
• Format: Hardcover
• Copyright: 2007-06-18
• Publisher: Cambridge University Press

Summary

Pre-eclampsia is one of the leading causes of death and disability in mothers and babies. Over four million women worldwide will develop the disorder every year. This book, written by an international team of experts, focuses on both the scientific basis of pre-eclampsia and its management. The basic science section contains up-to-date reviews of the most exciting research developments in pre-eclampsia. The clinical chapters provide a comprehensive review of the pertinent literature, highlighting recent data and new ideas or developments in current management. There is a section in each chapter (where relevant) that deals with practical management, giving clinicians a formulated treatment plan that they can implement directly. The book will be of interest to all professionals interested in the reproductive sciences, and to obstetricians and physicians with an interest in pre-eclampsia.

Table of Contents

Trophoblast invasion in pre-eclampsia and other pregnancy disorders	p. 3
Development of the utero-placental circulation : purported mechanisms for cytotrophoblast invasion in normal pregnancy and pre-eclampsia	p. 20
In vitro models for studying pre-eclampsia	p. 37
Endothelial factors	p. 50
The renin - angiotensin system in pre-eclampsia	p. 78
Immunological factors and placentation : implications for pre-eclampsia	p. 92
Immunological factors and placentation : implications for pre-eclampsia	p. 103
The role of oxidative stress in pre-eclampsia	p. 121
Placental hypoxia, hyperoxia and ischemia - reperfusion injury in pre-eclampsia	p. 138
Tenney-Parker changes and apoptotic versus necrotic shedding of trophoblast in normal pregnancy and pre-eclampsia	p. 152
Dyslipidemia and pre-eclampsia	p. 164
Pre-eclampsia a two-stage disorder : what is the linkage? : are there directed fetal/placental signals?	p. 183
High altitude and pre-eclampsia	p. 195
The use of mouse models to explore fetal - meternal interactions underlying pre-eclampsia	p. 209
Prediction of pre-eclampsia	p. 215
Long-term implications of pre-eclampsia for maternal health	p. 232
Classilication and diagnosis of pre-eclampsia	p. 243
Measuring blood pressure in pregnancy and pre-eclampsia	p. 258
Immune maladaptation in the etiology of pre-eclampsia; an updated epidemiological perspective	p. 276
Genetics of pre-eclampsia and counseling the patient who developed pre-eclampsia	p. 295
Thrombophilias and pre-eclampsia	p. 305
Medical illness and the risk of pre-eclampsia	p. 325
The kidney and pre-eclampsia	p. 339
Management of mild pre-eclampsia	p. 357
Management of severe pre-eclampsia	p. 369
The differential diagnosis of pre-eclampsia and eclampsia	p. 380
Complications of pre-eclampsia	p. 406
Central nervous system findings in pre-eclampsia and eclampsia	p. 424
Pathogenesis and treatment of eclampsia	p. 437
Anesthesia for the pre-eclamptic patient	p. 451
Critical care management of severe pre-eclampsia	p. 476
The role of maternal and fetal Doppler in pre-eclampsia	p. 489
Pregnancy-induced hypertension - the effects on the newborn	p. 506
Medico-legal implications of the diagnosis of pre-eclampsia	p. 522
Table of Contents provided by Blackwell. All Rights Reserved.