Preterm Labour: Managing Risk in Clinical Practice

by Edited by Jane Norman , Ian Greer

• ISBN13: 9780521821865
• ISBN10: 052182186X
• Format: Hardcover
• Copyright: 2005-10-17
• Publisher: Cambridge University Press

Summary

This is a practical guide to the optimal clinical management of preterm labour, using the best available evidence. Preterm labour remains a challenge today, even with the latest developments summarised here. The editors and authors (mostly practising clinicians) are all actively involved in research into the mechanisms, aetiology, treatment and associated outcomes of preterm labour. The chapters are based on common clinical scenarios and each provides a comprehensive literature review followed by evidence-based recommendations on appropriate management. A summary of the pathophysiology of parturition is provided, and the obstetric scenarios cover management of threatened preterm labour, management of preterm premature ruptured membranes and management of preterm labour with specific complications (such as intrauterine growth restriction). Other chapters include the epidemiology, the prediction and the prevention of preterm labour. Anaesthetic and paediatric issues are explored in depth, and there are chapters on legal and organisational issues around preterm labour.

Table of Contents

Contributors	vii
Preface	x
J. E. Norman
I. A. Greer
The epidemiology of preterm labour and delivery	1	(25)
Peter Danielian
Marion Hall
Biology of preterm labour	26	(50)
Andrew Thomson
Jane Norman
Transcriptional regulation of labour-associated genes	76	(33)
Tamsin Lindstrom
Jennifer Loudon
Phillip Bennett
Fetal outcome following preterm delivery	109	(24)
Malcom Levene
Lawrence Miall
The prediction of preterm labour	133	(20)
Philip Owen
Fiona Mackenzie
Prevention of preterm labour	153	(18)
John Morrison
Nandini Ravikumar
Management of preterm premature ruptured membranes	171	(20)
Donald Peebles
Management of threatened preterm labour	191	(19)
Manu Vatish
Katie Groom
Phillip Bennett
Steven Thornton
Management of preterm labour with specific complications	210	(25)
Mark Kilby
David Somerset
Anaesthetic issues in preterm labour, and intensive care management of the sick parturient	235	(25)
Anne May
Chris Elton
Management of the preterm neonate	260	(47)
Richa Gupta
Michael Weindling
Organisation of high risk obstetric and neonatal services	307	(22)
Karl Murphy
Sara Twaddle
The management of pregnancy and labour	329	(35)
Sheila A. M. McLean
Sarah Elliston
Treating the preterm infant -- the legal context	364	(33)
Sarah Elliston
Index	397