Prevention of Progressive Chronic Renal Failure

by El Nahas, A. Meguid; Mallick, Netar P.; Anderson, Sharon A.

• ISBN13: 9780192622372
• ISBN10: 0192622374
• Format: Hardcover
• Copyright: 1993-05-20
• Publisher: Oxford University Press

Summary

This book provides in-depth coverage of one of the most exciting and rapidly evolving areas of nephrology. Written by a selection of international experts, it covers both the latest advances in experimental nephrology and the clinical aspects of progressive kidney disease. It describes the progress made over the last decade in understanding the pathogenesis of progressive kidney scarring. It explores a range of therapeutic interventions, both dietary and pharmacological, and reviews their impact upon various experimental models of chronic renal failure. Clinical aspects are next considered, and current knowledge of the natural history of diabetic and non-diabetic kidney disease is comprehensively reviewed. Finally, options for the prevention of progressive renal failure in humans are assessed - emphasizing the huge difference between the efficacy of experimental and clinical interventions. Synthesizing a decade of research and clinical investigation in an exciting field of medicine, it is a must for both clinical nephrologists and researchers.

Table of Contents

Mechanisms of progressive renal failure

The role of tubulo-interstitial processes in progressive renal disease

Mechanisms of progression: the role of vascular injury/sclerosis

Dietary interventions for progressive renal disease in experimental animal models

Pharmacological interventions for progressive renal disease in experimental animal models

The natural history of chronic renal failure

Natural history and potential prevention of diabetic nephropathy in insulin-dependent and non-insulin dependent diabetic patients

Clinical management of progressive chronic renal failure

Table of Contents provided by Publisher. All Rights Reserved.