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9781612097732

Principles of Free Radical Biomedicine: New Horizons

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  • ISBN13:

    9781612097732

  • ISBN10:

    1612097731

  • Format: Hardcover
  • Copyright: 2011-11-30
  • Publisher: Nova Science Pub Inc
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List Price: $195.00

Summary

Recent years have witnessed an avalanche of new knowledge implicating free radicals in virtually every aspect of biology and medicine. It is now axiomatic that the regulated accumulation of reactive oxygen species (ROS) contributes to organismal health and well-being and that ROS serve as signalling molecules involved in cell growth, differentiation, gene regulation, replicative senescence and apoptosis. This book is an interdisciplinary text broken up into three consecutive volumes on the biochemistry and cellular/molecular biology of free radicals, transition metals, oxidants and antioxidants, and the role of oxidative stress in human health and disease.

Table of Contents

Introduction
The evolution of oxidative stress
Oxygen radicals & related species
Nitric oxide & derived oxidants
Sulfur-centered radicals
Redox active metals: iron & copper
Protein oxidation
Lipid peroxidation
Lipid nitration
DNA oxidation
Methods of investigation of selected radical oxygen/nitrogen species in cell-free & cellular systems
Enzymatic generation of hypoxia & steady-state H2O2
Chemiluminescence detection of H2O2
Index
Table of Contents provided by Publisher. All Rights Reserved.

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