Principles of Hormone/Behavior Relations

by Pfaff; Rubin; Phillips

• ISBN13: 9780125531498
• ISBN10: 0125531494
• Edition: 1st
• Format: Hardcover
• Copyright: 2004-09-20
• Publisher: Elsevier Science

Summary

This text introduces underlying principles of the endocrine regulation of behavior in animals and humans. Every chapter begins by stating a principle, followed by specific examples of hormone actions derived from scientific experiments and clinical observations, and concludes with a few challenging unanswered questions. The reference source Hormones, Brain & Behavior identified this field as rapidly expanding within neurobiology and endocrinology. Now, this well-illustrated and referenced text will serve students from undergraduate school to medical school as they learn this new discipline. * Uniform presentation of material across all chapter, with each chapter addressing a key principle, illustrated by basic experimental and clinical examples * Includes user-friendly features such as boxed figures with extended captions and references, numerous clinical notes, and a comprehensive list of abbreviations * Illustrations highlight both the clinical and basic science information

Table of Contents

Introduction	xi
SECTION I Characterizing the Phenomena: Hormone Effects are Strong and Reliable
Hormones Can Both Facilitate and Repress Behavioral Responses	3	(22)
One Hormone Can have Many Effects: A Single Hormone Can Affect Complex Behaviors	25	(18)
Hormone Combinations Can be Important for Influencing an Individual Behavior	43	(18)
Hormone Metabolites Can be the Behaviorally Active Compounds	61	(12)
There are Optimal Hormone Concentrations: Too Much or Too Little Can be Damaging	73	(20)
Hormones Do Not ``Cause'' Behavior; They Alter Probabilities of Responses to Given Stimuli	93	(12)
SECTION II History: Hormone Effects Can Depend on Family, Gender, and Development
Familial/Genetic Dispositions to Hormone Responsiveness Can Influence Behavior	105	(14)
The Sex of the Recipient can Influence the Behavioral Response	119	(12)
Hormone Actions Early in Development Can Influence Hormone Responsiveness in the CNS During Adulthood	131	(14)
Puberty Alters Hormone Secretion and Hormone Responsivity and Heralds Sex Differences	145	(10)
Changes in Hormone Levels and Responsiveness During Aging Affect Behavior	155	(16)
SECTION III Time: Hormonal Effects on Behavior Depend on Temporal Parameters
Duration of Hormone Exposure Can Make a Big Difference: In Some Cases Longer is Better; In Other Cases Brief Pulses are Optimal for Behavioral Effects	171	(10)
Hormonal Secretions and Responses are Affected by Biological Clocks	181	(16)
SECTION IV Space: Spatial Aspects of Hormone Administration and Impact are Important
Effects of a Given Hormone Can be Widespread Across the Body; Central Effects Consonant with Peripheral Effects Form Coordinated, Unified Mechanisms	197	(12)
Hormones Can Act at All Levels of the Neuraxis to Exert Behavioral Effects; The Nature of the Behavioral Effect Depends on the Site of Action	209	(12)
SECTION V Mechanisms: Molecular and Biophysical Mechanisms of Hormone Actions Give Clues to Future Therapeutic Strategies
In Responsive Neurons, Rapid hormone Effects Can Facilitate Later Genomic Actions	221	(10)
Gene Duplication and Splicing Products for Hormone Receptors in the CNS Often Have Different Behavioral Effects	231	(12)
Hormone Receptors and Other Nuclear Proteins Influence Hormone Responsiveness	243	(14)
SECTION VI Environment: Environmental Variables Influence Hormone/Behavior Relations
Hormone Effects on Behavior Depend Upon Context	257	(10)
Behavioral/Environmental Context also Alters Hormone Release	267	(16)
SECTION VII Evolution
Neuroendocrine Mechanisms Have Been Conserved to Provide Biologically Adaptive Body/Brain/Behavior Coordination	283	(12)
Further Reading	295	(28)
Acronyms	323	(4)
Index	327