Principles of Pharmacology: A Tropical Approach

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  • Edition: 1st
  • Format: Paperback
  • Copyright: 2009-10-29
  • Publisher: Cambridge University Press
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Supplemental Materials

What is included with this book?


This volume, first published in 1991, provides a useful and informative introduction to basic pharmacological principles and practice in the context of tropical medicine and diseases. The author discusses the cultural and environmental factors that affect the use of drugs in the tropics. The book highlights the potential inconsistencies and incompatibilities arising from the use of traditional and orthodox medicine, which can account for the extensive misuse of modern drugs among populations where the two systems are practised. Whilst emphasis is primarily given to the treatment of a wide range of tropical diseases, such as malaria, bilharzia and sickle-cell disease, the underlying principles are also fully explained to provide a conceptual framework for the academic exploration of cultural, genetic, environmental and nutritional factors affecting drug use in the tropics. The author also gives a concise treatment of systematic pharmacology. This makes the volume a useful text for students and practitioners of medicine and pharmacologists and specialists in tropical medicine, and for graduates studying chemotherapy of parasitic diseases. It will also be an important source of reference for medical and pharmacy students.

Table of Contents

General Background to Drug Usage in the Tropics:
Traditional medicine
The problems of availability and quality of modern drugs in the tropics
Fundamental Pharmacodynamic Principles:
Measurement of drug response
Receptors and drug response
Fundamental Principles in Drug Disposition:
Drug administration and factors affecting drug metabolism
Pharmacokinetic principles
Factors Affecting Drug Metabolism:
The influence of malnutrition and food-derived intoxicants
Genetic factors affecting drug action
Selective Toxicity:
Antimicrobial drugs
Antiprotozoal drugs
Anticancer and antiviral drugs
Drug resistance
Strategies for the development of new drugs
Systematic Pharmacology:
Drug targets in the nervous system
Noradrenergic mechanisms
Cholinergic mechanisms
Pain and inflammation
Drugs acting on the central nervous system
Cardiovascular and renal systems
Haemopoietic system
Endocrine system
Local hormones (autocoids)
Table of Contents provided by Publisher. All Rights Reserved.

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