Principles and Practice of the Biologic Therapy of Cancer

by Rosenberg, Steven A.

• ISBN13: 9780781722728
• ISBN10: 0781722721
• Edition: 3rd
• Format: Hardcover
• Copyright: 2000-05-01
• Publisher: Lippincott Williams & Wilkins

Summary

National Institutes of Health, Bethesda, MD. Provides scientific background and practical information required to understand and apply developments in the field. Designed to present state-of-the-art information to both research scientists and clinicians involved in development and application of new cancer treatments. Previous edition: c1995. DNLM: Neoplasms--therapy.

Table of Contents

Contributing Authors	ix
Preface	xvii
SECTION I: PRINCIPLES AND PRACTICE OF CYTOKINE THERAPY	1	(302)
Interleukins: Overview	3	(16)
Scott K. Durum
Interleukin-2: Preclinical Trials	19	(13)
Richard J. Barth, Jr.
James J. Mule
Interleukin-2: Clinical Applications	32	(61)
Principles of Administration and Management of Side Effects	32	(18)
Douglas J. Schwartzentruber
Melanoma	50	(23)
Michael B. Atkins
Arun Shet
Jeffrey A. Sosman
Renal Cell Carcinoma	73	(10)
James Chung-Yin Yang
Hematologic Malignancies	83	(10)
Alexander Fefer
Interleukin-4: Clinical Applications	93	(10)
Hideho Okada
Michael T. Lotze
Interleukin-12: Clinical Applications	103	(10)
Hideaki Tahara
Michael T. Lotze
Colony-Stimulating Factors: Basic Principles and Preclinical Studies	113	(28)
Malcolm A. S. Moore
Colony-Stimulating Factors: Clinical Applications	141	(33)
Colony-Stimulating Factors in Oncology	141	(11)
John A. Glaspy
Platelet-Stimulating Factors	152	(11)
Kenneth Kaushansky
Erythropoietin Therapy for the Cancer Patient	163	(11)
John A. Glaspy
Tumor Necrosis Factor: Basic Principles and Clinical Applications in Systemic and Regional Cancer Treatment	174	(20)
H. Richard Alexander, Jr.
Andrew L. Feldman
Interferon-α and -β: Basic Principles and Preclinical Studies	194	(15)
Bryan R. G. Williams
Interferon -α and -β: Clinical Applications	209	(77)
Leukemias, Lymphoma, and Multiple Myeloma	209	(15)
Moshe Talpaz
Farhad Ravandi
Razelle Kurzrock
Zeev Estrov
Hagop M. Kantarjian
Melanoma	224	(28)
John M. Kirkwood
Renal Cell Cancer	252	(13)
Christopher Tretter
Paul D. Savage
Hyman B. Muss
Marc S. Ernstoff
Kaposi's Sarcoma	265	(10)
Susan E. Krown
Epithelial Cancers	275	(11)
Sanjiv S. Agarwala
Interferon -γ: Basic Principles and Clinical Applications	286	(17)
Vijay Shankaran
Robert D. Schreiber
SECTION II: PRINCIPLES AND PRACTICE OF CELL TRANSFER THERAPY	303	(66)
Cell Transfer Therapy: Basic principles and preclinical Studies	305	(17)
Mark E. Dudley
Cell Transfer Therapy: Clinical Applications	322	(47)
Melanoma	322	(11)
Steven A. Rosenberg
Renal Cell Carcinoma	333	(13)
Arie S. Belldegrun
Robert A. Figlin
Belur Patel
Allogeneic Graft-Versus-Leukemia and Antitumor Effects	346	(11)
John Barrett
Adoptive Cellular Immunotherapy for Epstein-Barr Virus-Associated Malignancies	357	(12)
Malcolm K. Brenner
Helen E. Heslop
Cliona M. Rooney
SECTION III: PRINCIPLES AND PRACTICE OF MONOCLONAL ANTIBODY THERAPY	369	(122)
Monoclonal Antibodies: Basic Principles	371	(42)
Basic Concepts and Antigens Recognized	371	(11)
Kenneth A. Foon
Immunotoxins and Recombinant Immunotoxins	382	(14)
Lee H. Pai-Scherf
Robert J. Kreitman
Ira Pastan
Radioisotope Conjugates	396	(17)
Steven M. Larson
Chaitanya Divgi
George Sgouros
Nai-Kong V. Cheung
David A. Scheinberg
Monoclonal Antibodies: Clinical Applications	413	(78)
B-Cell Lymphomas	413	(15)
Scott M. Schuetze
David G. Maloney
T-Cell Leukemia and Lymphoma	428	(11)
Thomas A. Waldmann
Melanoma	439	(13)
Paul B. Chapman
Alan N. Houghton
Breast Cancer and Other Adenocarcinomas	452	(23)
Margaret von Mehren
Louis M. Weiner
Monoclonal Antibodies Directed Against Growth Factor Receptors	475	(16)
Jose Baselga
John Mendelsohn
SECTION IV: PRINCIPLES AND PRACTICE OF CANCER VACCINES	491	(240)
Cancer Vaccines: Cancer Antigens	493	(78)
Shared Tumor-Specific Antigens	493	(11)
Thierry Boon
Benoit J. Van den Eynde
Differentiation Antigens	504	(10)
Paul F. Robbins
Viral Antigens	514	(12)
Sjoerd H. van der Burg
Rienk Offringa
Cornelis J. M. Melief
Oncogenes and Mutations	526	(15)
Jay A. Berzofsky
Lee J. Helman
David P. Carbone
Carbohydrate Antigens on Glycolipids and Glycoproteins	541	(8)
Philip O. Livingston
Kenneth O. Lloyd
Glycoprotein Antigens	549	(8)
Olivera J. Finn
Identification of Human Tumor Antigens by Scrological Expression Cloning	557	(14)
Yao-Tseng Chen
Matthew J. Scanlan
Yuichi Obata
Lloyd J. Old
Cancer Vaccines: Basic Principles	571	(61)
General Concepts and Preclinical Studies	571	(13)
Nicholas P. Restifo
Immune Adjuvants	584	(17)
Michael L. Salgaller
Mechanisms of Immune Escape and Immune Tolerance	601	(16)
Francesco M. Marincola
Principles of Immune Monitoring in Cancer Vaccine Trials	617	(15)
Mario Sznol
Francesco M. Marincola
Cancer Vaccines: Clinical Applications	632	(99)
Whole Cell and Lysate Vaccines	632	(15)
Muthukumaran Sivanandham
Christos I. Stavropoulos
Marc K. Wallack
Genetically Modified Tumor Vaccines	647	(15)
Drew M. Pardoll
Elizabeth M. Jaffee
Peptides and Protein Vaccines	662	(12)
Steven A.Rosenberg
DNA Vaccines	674	(12)
Stephen A. White
Robert M. Conry
Recombinant Poxvirus Vaccines	686	(8)
Jeffrey Schlom
Dennis Panicali
Adenovirus and Other Viral Vaccines	694	(11)
Bruce Roberts
Dendritic Cell Vaccines	705	(16)
Ramsey M. Dallal
Robbie Mailliard
Michael T. Lotze
Vaccines Against Carbohydrate Antigens on Glycolipids and Glycoproteins	721	(10)
Philip O. Livingston
Govindaswami Ragupathi
SECTION V: PRINCIPLES AND PRACTICE OF GENE THERAPY	731	(94)
Basic Principles of Gene Therapy	733	(24)
Basic Principles and Safety Considerations	733	(14)
Kenneth G. Cornetta
Michael J. Robertson
Gene Transfer into Mammalian Cells	747	(10)
Susan A. Zullo
Natasha J. Caplen
Richard A. Morgan
Gene Therapy: Clinical Applications	757	(68)
Gene Therapy Using Lymphocyte Modification	757	(12)
Patrick Hwu
Gene Therapy Using Stem Cell Modification	769	(12)
Albert Deisseroth
Jo Hong Won
Lixin Zhang
Xue Yuen Peng
Takuma Fujii
Tao Wang
X. Y. David Guo
Allon Canaan
S. Shrimdkandada
Frank Hsieh
Andres Canova
Suicide Gene Therapy	781	(15)
David L. Bartlett
J. Andrea McCart
Gene Therapy Using Direct in Vivo Gene Injection	796	(15)
Bingliang Fang
Jack A. Roth
Antisense Oligodeoxynucleotides	811	(14)
Irina Lebedeva
C. A. Stein
SECTION VI: PRINCIPLES AND PRACTICE OF ANTIANGIOGENIC THERAPY	825	(38)
Antiangiogenesis: Basic Principles and Preclinical Models	827	(17)
Michael S. O'Reilly
Antiangiogenesis: Clinical Applications	844	(19)
Steven K. Libutti
James M. Pluda
SECTION VII: EVOLVING APPROACHES TO BIOLOGIC THERAPY	863	(34)
Delivery of Biologic Molecules and Cells to Tumors	865	(10)
Rakesh K. Jain
Flt-3 and Flt-3 Ligand	875	(15)
Eugene Maraskovsky Steward D. Lyman
Charles R. Maliszewski
David H. Lynch
CTLA-4 Blockade in Tumor Immunotherapy	890	(7)
James P. Allison
Arthur A. Hurwitz
Andrea van Elsas
Eugene Kwon
Timothy Sullivan
Barbara Foster
Norman Greenberg
Index	897