Principles and Practice of Gynecologic Oncology

by Hoskins, William J.; Perez, Carlos A.; Young, Robert C.

• ISBN13: 9780397515639
• ISBN10: 0397515634
• Edition: 2nd
• Format: Hardcover
• Copyright: 1996-12-01
• Publisher: Lippincott Williams & Wilkins

Summary

This updated Fourth Edition provides comprehensive coverage of the biology of gynecologic cancer, the therapeutic modalities available, and the diagnosis and treatment of site-specific malignancies. Because of the importance of multimodality treatment, the site-specific chapters are co-authored by a surgical oncologist, a medical oncologist, a radiation oncologist, and a pathologist. A significant portion of this edition focuses on monoclonal antibodies, vaccines, and gene directed therapies and how they can greatly improve treatment outcomes. A new chapter on end-of-life care is also included. Three distinguished new editors-Richard R. Barakat, MD, Maurie Markman, MD, and Marcus E. Randall, MD-now join the editorial team.

Table of Contents

Contributing Authors	p. xi
Preface	p. xvii
Acknowledgments	p. xix
Epidemiology of Gynecologic Cancers	p. 1
Epidemiology of Gynecologic Cancers	p. 3
Clinical Genetics of Gynecologic Cancer	p. 33
The Biology of Gynecologic Cancer	p. 39
Tumor Angiogenesis and Metastasis: Biology and Clinical Experience	p. 73
Oncogenes and Tumor-Suppressor Genes	p. 93
Immunotherapy of Gynecologic Malignancies	p. 123
Development and Identification of Tumor Markers	p. 157
Cancer Prevention Strategies	p. 179
Clinical Trials Methodology and Biostatistics	p. 199
Diagnostic Imaging Techniques in Gynecologic Oncology	p. 223
Therapeutic Modalities and Related Subjects	p. 267
Perioperative and Critical Care	p. 269
Surgical Principles in Gynecologic Oncology	p. 311
Laparoscopic Surgery in Gynecologic Cancer	p. 333
Biologic and Physical Aspects of Radiation Oncology	p. 375
Principles of Chemotherapy in Gynecologic Cancer	p. 461
Pharmacology and Therapeutics in Gynecologic Cancer	p. 489
Hormones and Human Malignancies	p. 561
Innovative Twenty-first Century Therapies	p. 587
Disease Sites	p. 625
Pathogenesis and Diagnosis of Preinvasive Lesions of the Lower Genital Tract	p. 627
Vulva	p. 665
Vagina	p. 707
Uterine Cervix	p. 743
Corpus: Epithelial Tumors	p. 823
Corpus: Mesenchymal Tumors	p. 873
Epithelial Ovarian Cancer	p. 895
Ovarian Germ Cell Tumors	p. 989
Ovarian Sex Cord-Stromal Tumors	p. 1011
Carcinoma of the Fallopian Tube	p. 1035
Gestational Trophoblastic Diseases	p. 1055
Breast Cancer	p. 1077
Special Management Topics	p. 1171
Management of Infections in Gynecologic Cancer Patients	p. 1173
Management of Late Effects of Gynecologic Cancer Treatment	p. 1193
Management of Pain	p. 1215
Rehabilitation as an Integrative Model: Psychologic and Surgical Approaches	p. 1241
Nutritional Support of Patients with Gynecologic Cancers	p. 1263
Cancer in the Pregnant Patient	p. 1279
AIDS and Women	p. 1313
Quality of Life Issues in Gynecologic Cancer	p. 1333
End of Life Care	p. 1343
Source Information on International, National, and Grant-Making Organizations of Relevance to Gynecologic Oncology	p. 1361
Index	p. 1367
Table of Contents provided by Rittenhouse. All Rights Reserved.