Principles and Practice of Gynecologic Oncology

by Hoskins, William J.

• ISBN13: 9780781719780
• ISBN10: 078171978X
• Format: Hardcover
• Copyright: 2000-09-01
• Publisher: Lippincott Williams & Wilkins

Summary

This updated Fourth Edition provides comprehensive coverage of the biology of gynecologic cancer, the therapeutic modalities available, and the diagnosis and treatment of site-specific malignancies. Because of the importance of multimodality treatment, the site-specific chapters are co-authored by a surgical oncologist, a medical oncologist, a radiation oncologist, and a pathologist. A significant portion of this edition focuses on monoclonal antibodies, vaccines, and gene directed therapies and how they can greatly improve treatment outcomes. A new chapter on end-of-life care is also included. Three distinguished new editors-Richard R. Barakat, MD, Maurie Markman, MD, and Marcus E. Randall, MD-now join the editorial team.

Table of Contents

Contributing Authors	xi
Preface	xix
Acknowledgments	xxi
Section I: Basic Science of Gynecologic Oncology
Epidemiology of Gynecologic Cancers	3	(26)
Louise A. Brinton
Robert N. Hoover
Genetics of Gynecologic Cancer	29	(26)
Henry T. Lynch
Jane F. Lynch
Murray Joseph Casey
Chhanda Bewtra
Steven A. Narod
Basic Biology and Biochemistry of Gynecologic Cancer	55	(32)
G. Scott Rose
Jay W. Carlson
Michael J. Birrer
Tumor Angiogenesis and Metastasis	87	(16)
Monica R. Brown
Laura Masiero
Elise C. Kohn
Oncogenes and Tumor-Suppressor Genes	103	(26)
Jeff A. Boyd
Thomas C. Hamilton
Andrew Berchuck
Immunology and Immunotherapy of Gynecologic Cancer	129	(36)
Michael A. Bookman
Matthew P. Boente
Robert C. Bast
Tumor Markers	165	(18)
Usha Menon
Ian J. Jacobs
Cancer Prevention	183	(16)
Paul F. Engstrom
Frank L. Meyskens
Hormonal Interactions in Gynecologic Malignancies	199	(26)
Edward S. Podczaski
Pondichery G. Satyaswaroop
Rodrigue Mortel
Biostatistics and Clinical Trials	225	(20)
Brian Bundy
Mark Brady
Section II: Therapeutic Modalities and Related Subjects
Surgical Principles in Gynecologic Oncology	245	(20)
Dennis S. Chi
Donald G. Gallup
Laparoscopic Surgery in Gynecologic Cancer	265	(32)
Daniel F. Dargent
Marie Plante
Perioperative and Critical Care	297	(30)
Hervy E. Averette
Mike F. Janicek
Thomas E. Nolan
Biologic and Physical Aspects of Radiation Oncology	327	(76)
Carlos A. Perez
Eric J. Hall
James A. Purdy
Jeffrey F. Williamson
Principles of Chemotherapy in Gynecologic Cancer	403	(22)
Michael A. Bookman
Robert C. Young
Pharmacology and Therapeutics in Gynecologic Cancer	425	(68)
David S. Alberts
Lisa A. Speicher
Dava J. Garcia
Robert T. Dorr
Daniel D. Von Hoff
Gynecologic Oncology for the General Obstetrician-Gynecologist	493	(8)
Kenneth L. Noller
Robert D. Hilgers
Mercedes Castiel
Cancer in the Pregnant Patient	501	(28)
Barbara A. Goff
Pamela J. Paley
Wui-Jin Koh
Stephen H. Petersdorf
James G. Douglas
Benjamin E. Greer
Management of Infections in Gynecologic Cancer Patients	529	(20)
Kent A. Sepkowitz
David L. Hemsell
Donald Armstrong
Management of Pain	549	(22)
Russell K. Portenoy
Pauline Lesage
Quality of Life among Women with Gynecologic Malignancies	571	(16)
David Cella
Beth Calhoun
Phillip Roland
Rehabilitation as an Integrative Model: Surgical and Psychological Approaches	587	(24)
Paul Georg Knapstein
Sabine Hawighorst-Knapstein
Christian Stief
Nutritional Support of Patients with Gynecologic Cancers	611	(18)
Mark A. Schattner
Moshe Shike
Diagnostic Imaging Techniques in Gynecologic Oncology	629	(40)
Susan M. Ascher
Izumi Imaoka
Hevig Hricak
Management of Late Effects of Treatment	669	(24)
David G. Mutch
Perry W. Grigsby
Maurie Markman
Stephen C. Rubin
AIDS and Women	693	(30)
Kevin B. Knopf
Otis W. Brawley
Section III: Disease Sites
National Strategies for Gynecologic Cancer	723	(12)
Edward L. Trimble
Michael A. Friedman
Pathogenesis and Diagnosis of Preinvasive Lesions of the Lower Genital Tract	735	(40)
Thomas C. Wright, Jr.
Vulva	775	(36)
Thomas W. Burke
Patricia J. Eifel
William P. McGuire
Edward J. Wilkinson
Vagina	811	(30)
Carlos A. Perez
Deborah J. Gersell
William P. McGuire
Mitchell Morris
Uterine Cervix	841	(78)
Frederick B. Stehman
Carlos A. Perez
Robert J. Kurman
James Tate Thigpen
Corpus: Epithelial Tumors	919	(42)
Richard R. Barakat
Perry W. Grigsby
Paul Sabbatini
Richard J. Zaino
Corpus: Mesenchymal Tumors	961	(20)
John P. Curtin
John J. Kavanagh
Harold Fox
William J. Spanos
Epithelial Ovarian Cancer	981	(78)
Robert F. Ozols
Stephen C. Rubin
Gillian M. Thomas
Stanley J. Robboy
Ovarian Germ-Cell Tumors	1059	(16)
Stephen D. Williams
David M. Gershenson
Carolyn J. Horowitz
Elvio Silva
Ovarian Sex Cord-Stromal Tumors	1075	(24)
Lynn C. Hartmann
Robert H. Young
Karl C. Podratz
Carcinoma of the Fallopian Tube	1099	(18)
Maurie Markman
Richard J. Zaino
Peter A. Fleming
Richard R. Barakat
Gestational Trophoblastic Diseases	1117	(22)
Ross S. Berkowitz
Donald P. Goldstein
Breast Cancer	1139	(102)
Beryl McCormick
Clifford Hudis
Alexandra Heerdt
Patrick I. Borgen
D. David Dershaw
Lee K. Tan
Carlos A. Perez
Marie E. Taylor
Index	1241