Principles and Practice of Gynecologic Oncology

by Hoskins, William J.; Perez, Carlos A.; Young, Robert C.; Barakat, Richard R.; Markman, Maurie; Randall, Marcus E.

• ISBN13: 9780781746892
• ISBN10: 0781746892
• Edition: 4th
• Format: Hardcover
• Copyright: 2004-09-15
• Publisher: LWW

Summary

This updated Fourth Edition provides comprehensive coverage of the biology of gynecologic cancer, the therapeutic modalities available, and the diagnosis and treatment of site-specific malignancies. Because of the importance of multimodality treatment, the site-specific chapters are co-authored by a surgical oncologist, a medical oncologist, a radiation oncologist, and a pathologist. A significant portion of this edition focuses on monoclonal antibodies, vaccines, and gene directed therapies and how they can greatly improve treatment outcomes. A new chapter on end-of-life care is also included. Three distinguished new editors--Richard R. Barakat, MD, Maurie Markman, MD, and Marcus E. Randall, MD--now join the editorial team.

Table of Contents

Contributing Authors	xi
Preface	xvii
Acknowledgments	xix
Section I. Epidemiology of Gynecologic Cancers	1	(266)
Epidemiology of Gynecologic Cancers	3	(30)
Louise A. Brinton
James V. Lacey, Jr.
Mark E. Sherman
Clinical Genetics of Gynecologic Cancer	33	(6)
Steven A. Narod
The Biology of Gynecologic Cancer	39	(34)
Kristin K. Zorn
Ginger J. Gardner
Michael J. Birrer
Tumor Angiogenesis and Metastasis: Biology and Clinical Experience	73	(20)
Edwin M. Posadas
Elise C. Kohn
Oncogenes and Tumor-Suppressor Genes	93	(30)
Jeff Boyd
Andrew Berchuck
Immunotherapy of Gynecologic Malignancies	123	(34)
David Z. Chang
Paul J. Sabatini
Chaitanya R. Divgi
Philip O. Livingston
Alan N. Houghton
Development and Identification of Tumor Markers	157	(22)
Karina Reynolds
Usha Menon
Ian Jacobs
Cancer Prevention Strategies	179	(20)
Paul F. Engstrom
Frank L. Meyskens
Clinical Trials Methodology and Biostatistics	199	(24)
Brian Bundy
Mark Brady
Diagnostic Imaging Techniques in Gynecologic Oncology	223	(44)
S.M. Ascher
C. Cooper
L. Scoutt
I. Imaoka
H. Hricak
Section II. Therapeutic Modalities and Related Subjects	267	(358)
Perioperative and Critical Care	269	(42)
James J. Burke, II
Janet L. Osborne
Christopher K. Senkowski
Surgical Principles in Gynecologic Oncology	311	(22)
Dennis S. Chi
Donald G. Gallup
Laparoscopic Surgery in Gynecologic Cancer	333	(42)
Daniel F. Dargent
Marie Plante
Yukio Sonoda
Biologic and Physical Aspects of Radiation Oncology	375	(86)
Carlos A. Perez
James A. Purdy
Zuofeng Li
E. J. Hall
Principles of Chemotherapy in Gynecologic Cancer	461	(28)
Michael A. Bookman
Pharmacology and Therapeutics in Gynecologic Cancer	489	(72)
David S. Alberts
Lisa M. Hess
Daniel D. Von Hoff
Robert T. Dorr
Hormones and Human Malignancies	561	(26)
Amir A. Jazaeri
G. Larry Maxwell
Laurel W. Rice
Innovative Twenty-first Century Therapies	587	(38)
Eric K. Rowinsky
Arno J. Mundt
Nadeem R. Abu-Rustum
Section III. Disease Sites	625	(546)
Pathogenesis and Diagnosis of Preinvasive Lesions of the Lower Genital Tract	627	(38)
Thomas C. Wright, Jr.
Vulva	665	(42)
David H. Moore
Wui-Jin Koh
William P. Mcguire
Edward J. Wilkinson
Vagina	707	(36)
Higinia R. Cardenes
Lawrence M. Roth
William P. McGuire
Katherine Y. Look
Uterine Cervix	743	(80)
Marcus E. Randall
Helen Michael
Jan Vermorken
Fred Stehman
Corpus: Epithelial Tumors	823	(50)
Claes G. Trope
Kaled M. Alektiar
Paul J. Sabbatini
Richard J. Zaino
Corpus: Mesenchymal Tumors	873	(22)
Gregory Sutton
John Kavanagh
Aaron Wolfson
Carmen Tornos
Epithelial Ovarian Cancer	895	(94)
Robert F. Ozols
Stephen C. Rubin
Gillian M. Thomas
Stanley J. Robboy
Ovarian Germ Cell Tumors	989	(22)
Daniela E. Matei
Anthony H. Russell
Carolyn J. Horowitz
David M. Gershenson
Elvio Silva
Ovarian Sex Cord-Stromal Tumors	1011	(24)
David M. Gershenson
Lynn C. Hartmann
Robert H. Young
Carcinoma of the Fallopian Tube	1035	(20)
Maurie Markman
Richard J. Zaino
Peter A. Fleming
Mary L. Gemignani
Gestational Trophoblastic Diseases	1055	(22)
Ross S. Berkowitz
Donald P. Goldstein
Breast Cancer	1077	(94)
Beryl M. McCormick
Clifford Hudis
Mary Gemignani
D. David Dershaw
Lee K. Tan
Carlos A. Perez
Marie E. Taylor
Section IV. Special Management Topics	1171	(190)
Management of Infections in Gynecologic Cancer Patients	1173	(20)
Kent A. Sepkowitz
David L. Hemsell
Donald Armstrong
Management of Late Effects of Gynecologic Cancer Treatment	1193	(22)
David G. Mutch
Perry W. Grigsby
Maurie Markman
Stephen C. Rubin
Management of Pain	1215	(26)
Russell K. Portenoy
Annette Vielhaber
Pauline Lesage
Rehabilitation as an Integrative Model: Psychologic and Surgical Approaches	1241	(22)
Paul-George Knapstein
Sabine Hawighorst-Knapstein
Christian Stief
Michael Krychman
Douglas A. Levine
Nutritional Support of Patients with Gynecologic Cancers	1263	(16)
Moshe Shike
Mark Schattner
Cancer in the Pregnant Patient	1279	(34)
Ron E. Swensen
Barbara A. Goff
Wui-Jin Koh
Stephen J. Petersdorf
James G. Douglas
Elizabeth M. Swisher
Benjamin E. Greer
AIDS and Women	1313	(20)
Mary Jo Lechowicz
Otis W. Brawley
Quality of Life Issues in Gynecologic Cancer	1333	(10)
Lari B. Wenzel
David Cella
End of Life Care	1343	(18)
Joanna M. Cain
Peter A. Heintz
Nikkie B. Swarte
Appendix Source Information on International, National, and Grant-Making Organizations of Relevance to Gynecologic Oncology	1361	(6)
Edward L. Trimble
Sergio Pecorelli
Index	1367