Product Design and Engineering Best Practices, 2 Volume Set

by Brö; ckel, Ulrich; Meier, Willi; Wagner, Gerhard

• ISBN13: 9783527315291
• ISBN10: 3527315292
• Edition: 1st
• Format: Hardcover
• Copyright: 2007-04-09
• Publisher: Wiley-VCH

Summary

Recommended reading for process, pharma and chemical engineers, chemists in industry, and those working in the pharmaceutical, food, cosmetics, dyes and pigments industries.

Author Biography

Prof. Ulrich Brockel studied Chemical Engineering at the Technical University of Karlsruhe, and finished his doctorate at the Institute of Mechanical Engineering in 1991. After his industrial carreer at the BASF process engineering department - heading a team responsible for agglomeration and product design of solids - he became Professor at the University of Applied Sciences Trier in 2000. He is member of APV (Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik), DECHEMA (Gesellschaft fur Chemische Technik und Biotechnologie, GVC (VDI-Gesellschaft Verfahrenstechnik und Chemieingenieurwesen), and he is co-chairing the section group "Product Design and Engineering" of the EFCE (European Federation of Chemical Engineering). Professor Brockel's work focuses on solids processing and plant design.

Dr. Gerhard Wagner studied Chemical Engineering at the Technical University of Munich. After gaining his PhD from the Technical University Munich, he worked as a scale up engineer in the chemical process development department of Hoffmann-La Roche in Basle, Switzerland. Currently he is responsible for the form development research and development department. Gerhard Wagner is member of the SPIN (Solid Processing Industrial Network) and the section group "Product Design and Engineering" within the EFCE.

Dr. Willi Meier studied Chemistry at the RWTH Aachen, where he gained his PhD in 1992. He is responsible for the international cooperation of the DECHEMA and he is coordinating the research activities of the section groups of the EFCE and the EFB (European Federation of Biotechnology).

Table of Contents

Preface

List of Contributors

Introduction

Why this Book?

Why is Chemical Product Design Important?

Structure ofthe Book Series

Interaction Forces between Particles

Introduction

Forces between Atoms and Molecules

Adhesion Forces between Particles, respectively Interfaces (Condensed Matter), in Gaseous Environment

Adhesion Forces in Aqueous Solution

Dynamic Adhesive Forces

Measurements ofAdhesion Forces between Particles

Fundamentals of Crystallization

Abstract

Introduction

Fundamentals ofCry stallization

Solids

Quantifying Particle Properties

Emulsification Techniques for the Formulation of Emulsions and Suspensions

Abstract

Motivation

Emulsion Basics

Emulsification Processes

Emulsification Process Functions

Scale up ofEm ulsification Processes Using Process Functions

Applications in the Product Design ofSolids

Outlook

Characterization of Disperse Systems

Abstract

Introduction

Properties ofDisp erse Systems and their Relevance for Process Engineering

Measuring Methods for Particle Properties

Measuring Process Technology

Online Characterization

Outlook

Introduction to Technologies Used for Structuring Chemical Products

Abstract

Introduction

Agglomerated Products

Processes for Making Agglomerated Products

Soft Solids

Future Developments

Product Design by Spray Drying

Introduction

Fundamentals

Control ofProduct Properties by Design and Operation of Spray-drying Equipment

Conclusions

Wet Granulation in Agitated Processes

Introduction

Theory ofGran ulation

Types ofGran ulators

Compaction

Fundamentals

Roller Press

Tableting

Extrusion Technology for Product Design

Abstract

Introduction

Anatomy of Extruders

Design of Screw Configurations for Food Extrusion

Die Assembly

Systems Analytical Approach to Extrusion

Modeling Food Extrusion

Outlook

Manufacturing of Pharmaceutical Dosage Forms using Melt-extrusion Technology

Abstract

Tablet-manufacturing Technologies

Manufacturing Technologies Involving Melt Processing

Melt Processing ofPharm ac

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