Prognostic and Predictive Factors in Breast Cancer

by Walker, Rosemary A.

• ISBN13: 9781841843001
• ISBN10: 1841843008
• Format: Hardcover
• Copyright: 2003-06-12
• Publisher: Informa Healthc

Summary

This title reviews the key prognostic factors in breast cancer, discussing the methodologies involved in measuring and reporting. It also examines the roles of major predictive markers such as the steroid receptors, p53 and HER-2. Given the wealth of information in the medical literature on breast cancer, this volume is useful in that it focuses strictly on these factors. That focus makes this text extremely useful for oncologists and researchers who want to learn more about best practices in prognoses.

Table of Contents

Contributors	vii
Prognostic and predictive factors in breast cancer: An overview	1	(6)
Rosemary A Walker
The role of the pathologist in assessing prognostic factors for breast cancer	7	(16)
Gavin C Harris
Sarah E Pinder
Christopher W Elston
The determination and significance of occult axillary lymph node metastases in breast cancer	23	(16)
Andrew HS Lee
Risk factors for local recurrence following conservation therapy in breast cancer	39	(18)
Paula HM Elkhuizen
Marc J van de Vijver
Prognostic value of proliferation and apoptosis in breast cancer	57	(28)
Paul J van Diest
Johannes S de Jong
Jan PA Baak
Rob Jam Michalides
Elsken van der Wall
The role of cell adhesion molecules and matrix metalloproteinases in predicting breast cancer behaviour	85	(20)
J Louise Jones
Detection of minimal residual disease in predicting outcome in breast cancer	105	(16)
Stephan Braun
Klaus Pantel
Allelic imbalance and microsatellite instability in breast cancers and blood in determining breast cancer behaviour	121	(14)
Jacqueline Amanda Shaw
The use of steroid receptors in predicting response to hormonal therapy	135	(12)
Elizabeth Anderson
MAP kinase family members and endocrine response and survival in breast cancer	147	(20)
Iain R Hutcheson
Julia MW Gee
Robert I Nicholson
p53 and breast cancer	167	(26)
Dorin Ziyaie
Alastair M Thompson
Assessment of HER2 and its value in breast cancer	193	(22)
Rajan S Rampaul
Sarah E Pinder
John Fr Robertson
Ian O Ellis
Index	215