Protein Engineering A Practical Approach

by Rees, Anthony R.; Sternberg, Michael J. E.; Wetzel, Ronald

• ISBN13: 9780199631391
• ISBN10: 0199631395
• Format: Spiral Bound
• Copyright: 1993-02-04
• Publisher: Oxford University Press

Summary

1. Methods of structural analysis of proteins - part 1 - protein crystallography, E.Y. Jones & D.I. Stuart


2. Methods of structural analysis of proteins - part 2 - nuclear magnetic resonance, G.M. Clore & A.M. Gronenborn


3. Mol

Table of Contents

Methods of Structural Analysis of Proteins -

Protein Crystallography

Methods of Structural Analysis of Proteins

Nuclear Magnetic Resonance

Molecular Sequence Data- Bases and Their Uses

Design of Protein Structures

From Protein Sequence to Structure

The Use of Theoretical Methods in Protein Engineering

Principles of protein stability - part 1 - reversible unfolding of proteins: kinetic and thermodynamic analysis

Principles of protein stability - part 2 - enhanced folding and stabilization of proteins by suppression of aggregation in vitro and in vivo

Principles of protein turnover: possible manipulations

Chemical approaches to expression of proteins

Protein engineering of antibody combining sites

Selection of variants of antibodies and other protein molecules using display on the surface of bacteriophage fd

Expression of proteins in prokaryotic systems - principles and 'case' studies

Expression of proteins in yeast

Genetic engineering of the processing and secretory pathway of an inflammatory cytokine in mammalian cells: a case study

Industrial applications of protein engineering and scale-up of protein production: l-antitrypsin, a case study

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