Protein Hydrolysates in Biotechnology

by Pasupuleti, Vijai K.; Demain, Arnold L.

• ISBN13: 9781402066733
• ISBN10: 1402066732
• Format: Hardcover
• Copyright: 2010-10-30
• Publisher: Springer Verlag

Summary

The protein hydrolysates industry is growing rapidly yet there is no single book that describes the challenges and opportunities for manufacturers and end users, techniques used in manufacturing, characterization and screening of protein hydrolysates, their applications in a wide variety of industries in biotechnology. One of the misconceptions in using protein hydrolysates in fermentations is that the end user believes and uses it as a mere nitrogen source. However, the functionality of the product obtained is not necessarily due to protein hydrolysates alone because it may not be a pure peptide or a combination of peptides and may contain carbohydrates, lipids, micronutrients, etc., present in the raw material used or sometimes the manufacturers deliberately add to the process to bring unique functionality. Only a handful of manufacturers dictate this market that tend to keep manufacturing process proprietary making it harder to understand. This book will close the gap by unfolding information on latest developments.

Author Biography

Vijai K. Pasupuleti, Ph.D., is founder of SAI International that engages in research, consulting and marketing for biotechnology, pharmaceutical and nutraceutical companies. For almost two decades, he has been working with protein hydrolysates and bioactive peptides and has developed several new products. His main areas of research have been enzymatic hydrolysis of proteins and their applications in a wide range of industries. He is the co-editor of a book, author and co-author of several book chapters and publications. He has chaired and co-chaired several technical sessions on protein hydrolysates and bioactive peptides. Arnold L. Demain, Ph. D., is Research Fellow in Microbial Biochemistry in the Charles A. Dana Research Institute for Scientists Emeriti (R.I.S.E.) of Drew University. He has spent many years in the area of microbial production of primary and secondary metabolites of microorganisms. His experience includes 15 years at Merck and Co., Inc., 32 years at the Massachusetts Institute of Technology (MIT) and 9 years at Drew University. At Drew, he mentors undergraduate and high school students in microbial production of antibiotics and microbial sensitivity to cisplatin and related anticancer agents.

Table of Contents

Applications of Protein Hydrolysates in Biotechnology	p. 1
State of the Art Manufacturing of Protein Hydrolysates	p. 11
Towards an Understanding of How Protein Hydrolysates Stimulate More Efficient Biosynthesis in Cultured Cells	p. 33
Benefits and Limitations of Protein Hydrolysates as Components of Serum-Free Media for Animal Cell Culture Applications: Protein Hydrolysates in Serum Free Media	p. 55
Oligopeptides as External Molecular Signals Affecting Growth and Death in Animal Cell Cultures	p. 79
Use of Protein Hydrolysates in Industrial Starter Culture Fermentations	p. 91
Protein Hydrolysates from Non-bovine and Plant Sources Replaces Tryptone in Microbiological Media	p. 115
The Use of Protein Hydrolysates for Weed Control	p. 127
Physiological Importance and Mechanisms of Protein Hydrolysate Absorption	p. 135
Protein Hydrolysates/Peptides in Animal Nutrition	p. 179
Protein Hydrolysates as Hypoallergenic, Flavors and Palatants for Companion Animals	p. 191
The Development of Novel Recombinant Human Gelatins as Replacements for Animal-Derived Gelatin in Pharmaceutical Applications	p. 209
Index	p. 227
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